Now researchers have recognized a similar set of genes that can
distinguish aggressive prostate cancer.
Not exact matches
The researchers are now further investigating the possibility of using this approach on other
cancers, including
prostate cancer, where it could be used to
distinguish more
aggressive tumors from those that grow much more slowly, Bhatia says.
Since most men with
prostate cancer have indolent (non-
aggressive) disease for which conservative therapy or surveillance would be appropriate treatment, the clinical challenge is not only how to identify those with
prostate cancer, but also how to
distinguish those who would benefit from surgical or other
aggressive treatment from those who would not.
In a report published in the New England Journal of Medicine, scientists say that a panel of 20 genes can
distinguish the more common localized
prostate cancer that grows slowly and rarely spreads from the more
aggressive type that can spread quickly.
The findings also hint that in coming years, it may be possible to use the panel not just among men with advanced disease but to
distinguish between men who develop the slower growing type of
prostate cancer from the more
aggressive type.