Sentences with phrase «diverse roles in disease»

«tRFs are active in this mosquito and may play diverse roles in disease vector biology.»

Not exact matches

Characterization of this immensely diverse ecosystem is the first step in elucidating its role in health and disease.

«There is a growing appreciation for the role of diverse bacteria in contributing to improved health as well as triggering disease processes or exacerbating illness,» says Michael H. Hsieh, M.D., Ph.D., director of the Clinic for Adolescent and Adult Pediatric Onset Urology (CAPITUL) at Children's National Health System and study senior author.

It should radically transform our knowledge of immune function and dysfunction in infectious diseases, autoimmune or inflammatory disorders, and the role of immunocytes in other diseases as diverse as cancer, type 2 diabetes, and psychiatric disease.

At the NHMRC he played a crucial role in expanding Australia's participation in international research collaborations such as the International Cancer Genome Consortium and the Global Alliance for Chronic Disease research and by establishing many bilateral research funding agreements with HFSPO member countries and diverse funding organizations around the world including the Asia - Pacific region.

Oligodendrocytes, a type of brain cell that plays a crucial role in diseases such as multiple sclerosis, are more diverse than have previously been thought, according to a new study led by Sten Linnarsson, Karolinska Institutet / SciLifeLab and Gonçalo Castelo - Branco, Karolinska Institutet.

The diverse set of antagonists described in this article will be useful in guiding medicinal chemists to rationally design effective CXCR4 antagonists for the treatment of human diseases where SDF - 1 / CXCR4 axis plays a critical role.

The role of these molecules in driving disease pathology might vary, with described activities of HVEM signaling promoting T cell expansion or survival, analogous to certain activities of OX40 and 4 - 1BB, and other activities of HVEM or LTβR increasing the function of diverse cells such as stromal cells, dendritic cells, macrophages, eosinophils, epithelial cells and keratinocytes.

The Sette lab's research on DENV encompasses large - scale epitope identification (supported by an HHS contract) and diverse studies towards understanding the role of T cells and HLA variants in the development of (or protection from) DENV disease (supported in part by a consortium grant led by Eva Harris at UC Berkeley).

In light of the widespread role of oxidative stress in the pathology of diverse human diseases and the ability of the Nrf2 - dependent antioxidant response gene network to protect against oxidative stress, considerable effort has been directed towards discovering compounds that can increase the activity of NrfIn light of the widespread role of oxidative stress in the pathology of diverse human diseases and the ability of the Nrf2 - dependent antioxidant response gene network to protect against oxidative stress, considerable effort has been directed towards discovering compounds that can increase the activity of Nrfin the pathology of diverse human diseases and the ability of the Nrf2 - dependent antioxidant response gene network to protect against oxidative stress, considerable effort has been directed towards discovering compounds that can increase the activity of Nrf2.

Interestingly, it has been shown that the creatine / phosphocreatine pathway may play a central role in energy metabolism, and nutritional creatine supplementation has been shown to impart beneficial effects in a number of diverse disease pathologies (Kitzenberg et al., 2016).

They found that complement may, in part, be responsible for maintaining a diverse set of microbes on our skin and keeping our skin healthy, which could play a role in a host of skin diseases.