Sentences with phrase «division of the fertilized egg»
Embryonic development in mammals begins with the division of the fertilized egg, which is then followed by several further rounds of division to form the blastocyst, a sphere of cells made up of two layers of cells surrounding a fluid - filled cavity.
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But understanding the precisely orchestrated choreography that unfolds within each egg during cell division will eventually allow us to correct the errors, to ensure the production of healthy eggs that can be fertilized.
«Ladies, this is why fertility declines with age: Age - related female infertility explained by a defect in the choreography of chromosome sharing during cell division in eggs before they are fertilized.»
The film depicts several sperm attempting to fertilize the egg, «zooms in» on one sperm's tail to show how the dynein proteins move in sync to cause the tail to bend and flex, and ends with the sperm's successful journey into the egg and the initiation of cell division that will ultimately create a new organism.
«Maybe at the one - cell or two - cell stage,» Eggan and his colleagues reasoned, «there's still some of that stuff in there...» And if they picked the right moment of cell division, when these powerful reprogramming factors were still floating around in the periphery of the cell, they might be able to use drugs to temporarily freeze the cell in the middle of division, stick in the needle of a micromanipulator to suck out the embryonic DNA, squirt in DNA from an adult animal, and then kick - start the process of reprogramming — hours, perhaps even days after an egg had been fertilized.
Although the researchers had first removed the DNA of both the egg and the fertilizing sperm, the egg was still primed for cell division and development, increasing the chances of success, the team says.
Newly fertilized eggs before gene editing (left) and embryos after gene editing and a few rounds of cell division (right).
All embryos start from a fertilized egg, which, after completing its division process, leads to the formation of a blastocyst.