The addition of
docetaxel not only lengthened survival but delayed disease progression as measured by an increase in prostate - specific antigen (PSA), the appearance of new metastases, or worsening symptoms.
Not exact matches
Sengupta and his colleagues took breast cancer cells that did
not have the markings of CSCs and exposed them to
docetaxel, a common chemotherapy drug.
The majority of patients included in the study were
not eligible for
docetaxel because their disease had progressed despite pretreatment with this drug (approximately 57 %).
If
docetaxel treatment was
not an option for the patients or if the primary treatment goal was the relief of symptoms, the so - called «symptom control,» and the prevention of complications, the G - BA specified BSC as appropriate comparator therapy (BSC population).
When injected into the body,
docetaxel doesn't discriminate between healthy and cancerous cells.
«Biomarkers determining who will or will
not completely respond to neoadjuvant TCHP [trastuzumab, carboplatin,
docetaxel, and pertuzumab] are lacking,» wrote study authors led by Jeremy Force, DO, of Duke University School of Medicine in Durham, North Carolina.
However, subset analyses of phase III trials suggest that patients with EGFR mutation - positive NSCLCs do
not benefit from immunotherapy compared with
docetaxel.
Inclusion Criteria: • The participant may have no more than 2 prior lines of systemic therapies (neoadjuvant and adjuvant therapies will
not be considered as a prior line of therapy) for advanced or metastatic disease and is suitable to receive gemcitabine and
docetaxel therapy.
A total of 28.9 % of patients receiving
docetaxel had
not progressed after 6 months, compared with 16.9 % of erlotinib patients.