Sentences with phrase «docetaxel treatment»

If docetaxel treatment was not an option for the patients or if the primary treatment goal was the relief of symptoms, the so - called «symptom control,» and the prevention of complications, the G - BA specified BSC as appropriate comparator therapy (BSC population).

It was assumed in the assessment that most of the remaining patients actively decided against docetaxel treatment.

The next generation drug in the taxane family, cabazitaxel, was approved in 2010, but only for patients whose cancer no longer responded to hormone therapy or docetaxel treatment.

If prolongation of life was the primary therapeutic objective and the patients were eligible for docetaxel treatment, the G - BA specified docetaxel in combination with prednisone or prednisolone as appropriate comparator therapy (docetaxel population).

Not exact matches

The team gave 137 women with breast cancer either T - DM1 or the standard treatment of Herceptin plus another drug, docetaxel.

The researchers showed that cabazitaxel worked better than docetaxel in human prostate cancer cells lines that were resistant hormone treatment, both in terms of slowing cancer - cell growth and in its ability to kill cancer cells.

No evaluable data were available for the comparison with docetaxel in patients in whom prolongation of life was the primary treatment goal.

For years, docetaxel has been the only effective chemotherapy for men whose cancer was no longer responding to hormone treatments.

In the 520 patients who had high - extent disease (whose cancer had spread to major organs and / or the bones), treatment with ADT plus docetaxel had an even greater benefit: these men had a median overall survival of 49.2 months versus 32.2 in the ADT - only group — a difference of 17 months.

CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or docetaxel in a transgenic mouse model.

RNA - sequencing dissects the transcriptome of polyploid cancer cells that are resistant to combined treatments of cisplatin with paclitaxel and docetaxel.

Combination of GHRH antagonists and docetaxel shows experimental effectiveness for the treatment of triplenegative breast cancers.

The U.S. drug maker released a statement on Monday saying that its Keynote - 010 study, a randomized Phase two - third trial, showed that patients who were taking two different doses of Keytruda (FDA - approved two mg / kg dose and treatment dose of 10 mg / kg given every three weeks) had longer survival compared to those who took docetaxel, the drug widely used for non-small cell lung cancer (NSCLC).

There was one treatment - related death in the erlotinib group, and 22.1 % of docetaxel patients and 29.0 % of erlotinib patients suffered adverse events that led to dose modification.

• The participant has received prior treatment with gemcitabine or docetaxel.

The drug's manufacturer, Roche, said trials in these patients have shown that giving pertuzumab in combination with the drugs trastuzumab (Herceptin) and docetaxel could extend survival by nearly 16 months compared to standard treatment.

Pertuzumab was approved by the FDA in 2012 for first - line treatment of HER2 + metastatic breast cancer in combination with trastuzumab and the chemotherapy docetaxel (Taxotere).