How
does regulation of gene expression determine inner ear function on a genetic and epigenetic level?
Not exact matches
Interestingly, this process involves the structures
of the Pax3 protein that bind to DNA, but this process
does not involve DNA binding or
regulation of gene expression.»
Out
of 24,389 OGSv2
gene models, we
did not detect any
expression in either sample for 2,950
genes and filter an additional 7,289
genes because
of low average
expression (leaving little or no power to infer differential
regulation for these
genes).
This last observation seems to indicate that promoter methylation
does not play a significant role in
regulation of gene expression between tissues.
Finally, because we
did not measure
gene expression, the current results await replication and extension using methods that can clarify whether the observed effects are associated with changes in
gene expression that would indicate up or down
regulation of TNF.