Sentences with phrase «dog genome»

Now that we have mapped the complete dog genome, genes involved in both disease and desired traits can be identified much more quickly.

«Analysis of dog genome will provide insight into human disease.»

Andrew Hogan [C] Samples Manager Dog Genome Project, NIH / NHGRI Email: This email address is being protected from spambots.

Ancient European dog genomes reveal continuity since the Early Neolithic.

Domesticating dogs from gray wolves more than 15,000 years ago involved artificial selection and inbreeding, but the effects of these processes on dog genomes have been little - studied.

The raccoon dog genomes also showed signs of a recent population expansion, suggesting their population had shrunk to a low level and then exploded.

Using the latest dog genome assembly and small RNA sequences of nine different dog tissues including skin, blood, ovaries and testes, scientists from TGAC have identified 91 novel miRNAs.

Dayna L. Dreger, PhD, a researcher with the National Institutes for Health NHGRI Dog Genome Project is asking for our help in collecting samples for researching the genetic variants for coat type and color in Chow Chows as well as leg conformation (genes that contribute to the normal leg structural variation across and within breeds).

With the recent decoding of the complete dog genome, this coincidence could aid the search for cures to many devastating types of illness.

And a dog genome sequence has made the animals an even more useful model by quickening the search for disease - causing genes.

Erik Axelsson of Uppsala University in Sweden and his colleagues analyzed DNA from 12 wolves and 60 dogs that represent 14 diverse breeds, looking for regions of the dog genome that evolved under selection pressure during domestication.

The dog genome has been sequenced, but we still don't know how it is controlled and regulated, what we call the epigenome.

A gene for the enzyme that splits starch into simpler sugars has replicated itself in the dog genome, and become more efficient — a sure sign that it is in demand.

At the same meeting, Kerstin Lindblad - Toh of the MIT Broad Institute in Cambridge, Massachusetts, and her colleagues outlined the initial analysis of the 2.4 billion bases of the dog genome.

Soon there will be another dog genome sequence to work with, this time of a boxer (bottom center).

This new line of research was made possible by the completion of the Dog Genome Project in 2005 by the National Human Genome Research Institute (NHGRI) in Bethesda, Maryland.

They sequenced everything in the sample, including contaminating DNA, then used a computer to pick out sequences averaging 70 base pairs which matched parts of the dog genome.

Dr Penso - Dolfin, added: «Our results represent a clear improvement in our knowledge of the dog genome, paving the way for further research on the evolution of gene regulation, and the contribution of microRNAs to pathological conditions.

New research published today in PLOS ONE reveals an improved annotation of microRNAs in the dog genome to further understand its biological role.

The cat genome has been mapped, just like the dog genome, and there are research tools out there,» explains Professor Lohi.

Floppy - eared breeds show sharply reduced heterozygosity, suggesting this region, the highest FST region in any autosomal segment of the dog genome (Table 1), has undergone strong selection for floppy ear position or perhaps some correlated trait.

«Strikingly the amylase gene is present in many more copies in the dog genome than in wolves.

To continually produce more extreme variation despite these purifying forces requires the dog genome to create new alleles at an extraordinary rate.

This inherent variety in the dog genome is how man has been able to create so many different breeds with characteristics as different as those noted between a Chihuahua and an Irish Wolfhound.

Luckily for Cyrus and other GSPs, the UC Davis Veterinary Medical Teaching Hospital is conducting a clinical trial to identify the region of the dog genome associated with CED in GSPs.

Many dog owners and many dogs have forgotten that although the dog genome is very plastic, dogs are still, in their most secret hearts and neurochemicals, predators.

We propose to identify the region of the dog genome associated with myopia in the Labrador retriever.

As leaders of the Dog Genome Project at the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH), we are writing to discuss a possible new collaboration with your breed club.

The argument succeeded, and the big announcement by Ostrander and her colleagues came in 2005 with a report in Nature: They had sequenced a dog genome belonging to a female boxer named Tasha.

Kerstin Lindblad - Toh, a professor in comparative genomics at the Broad Institute of Harvard and MIT as well as at Uppsalla University in Sweden, is one of the leaders in the effort to sequence the dog genome as a way to better understand human disease.

In fact, Ostrander, who works at the NHGRI's Cancer Genetics and Comparative Genomics Branch, was one of the lead authors of a white paper arguing for support to sequence the dog genome at a level of quality already available at the time for the mouse, «to better understand the genetic basis of complex diseases affecting both human and dog.»

«Using the dog genome sequence in combination with the human genome sequence will help researchers to narrow their search for many more of the genetic contributors underlying cancer and other major diseases.»

The dog genome contains approximately 3 billion base pairs of DNA and thousands of genes.

The dog genome is easier to parse for cancer - mapping studies because of the relatively closed genetic makeup of distinct breeds.

«To be honest, the last thing I expected them to say to me was, «Hey Carl, we've got a way to sequence dog genomes and tell you what the breed content of your dog is.»

Everts (2000) suggested a major gene model for fragmented coronoid process, which is one form of a growth disorder in the elbow joint, but approximately 80 % of the dog genome was excluded as a candidate region in a search of markers, under a hypothesis of a recessive inheritance.

first there is about 50 genes of the 20000 dog genome that decide its appearance.