Sentences with phrase «dog with the gene»

By dosing dogs with the gene for a myostatin precursor, Sweeney has found he can throw a wrench into the molecular machinery of myostatin signaling, removing a critical check on muscle growth and allowing deteriorating muscles to regain their strength.

Penn Vet researchers have had success in treating various forms of blindness in dogs with gene therapy, setting the stage to treat human blindness.

Given that some countries are now banning docking, breeders are again attempting to select for dogs with the genes for natural bob tails.

However, and this is a big point, it is not a given that a dog with this gene will have an adverse reaction if given any of these drugs.

Acepromazine (WSU vets recommend reducing the dose by 25 % in dogs that are heterozygous for the MDR1 gene, meaning they have one mutant and one normal gene, and 30 - 50 % in dogs with both genes mutant)

Dd = solid color (yellow, black, or chocolate) However a dog with this gene can produce dilute color puppies if it mates with another dog with either Dd or dd gene.

(In other words, the breeder should have refused to let dogs with the gene reproduce).

Generalized demodicosis is genetically predisposed, meaning the dog must have the necessary genes but not every dog with the genes gets the disease.

It may be autoimmune and all autoimmune diseases are genetically predisposed: The dog must have the genes to get the disease, but not every dog with the genes will become ill.

IBD may be autoimmune and all autoimmune diseases are genetically predisposed: The dog must have the genes to get the disease, but not every dog with the genes will become ill.

All autoimmune diseases are genetically predisposed: The dog must have the genes to get the disease, but not every dog with the genes will become ill.

Not all dogs with this gene will develop CCD, and there are certain circumstances which are more likely to instigate a behavior which can become compulsive.

How do these people convince the public that by combining two distinct breeds, they will produce a dog with genes that eliminate shedding and allergy problems?

Not exact matches

The team also looked at 56 genes that they had identified in a study of dogs with canine compulsive disorder, a condition in which dogs repeatedly chase their tails, pace back and forth, groom themselves or sucks things, sometimes for hours at a time.

Researchers who previously showed that a gene therapy treatment could save the lives of dogs with a deadly disease called myotubular myopathy — a type of muscular dystrophy that affects the skeletal muscles — have found that the therapy is long - lasting.

«It was kind of fun being at a medical school and known as the weird guy who worked with dogs,» says Modiano, who is now a professor of comparative oncology at the University of Minnesota College of Veterinary Medicine and the Masonic Cancer Center, where his research focuses on immunology, cancer cell biology, cancer genetics, and applications of gene therapy.

«Dogs have more than 20,000 genes with sophisticated immune and central nervous systems.

«The company has a real history of ingenious inventions — I think there must have been a bit of Wallace and Gromit in their genes, tempered of course with Swiss reliability,» says Mark Hill, vice-president of corporate communications, referring to the eccentric inventor and his dog created by animator Nick Park.

Work on gene therapy is showing significant progress for restoring muscle strength and prolonging lives in dogs with a previously incurable, inherited neuromuscular disease.

Four collaborating research groups in the United States and France found a way to safely replace the disease - causing MTM gene with a healthy gene throughout the entire musculature of affected dogs.

The dogs were chosen because they have inherited a genetic disease caused by the same gene defect as some patients with human retinitis pigmentosa.

However, not all dogs with the mutation became affected, prompting the hypothesis that additional genes could modify disease risk.

Geneticists have pinpointed the gene variant that imparts this black fur and determined that it comes from domestic dogs that interbred with their wily cousins thousands of years ago.

Not only do black - furred dogs and wolves have the same gene variant, but the DNA surrounding the K locus is also quite similar — and quite different from that of gray wolves — suggesting that the variant was introduced when wolves interbred with domestic dogs.

So geneticists have been focusing on the dog as a possible model for gene searches because this lack of sequence variation may help them circumvent a frequent problem with studies in humans.

Previous studies have suggested, among other things, that differences in dogs» ability to communicate are associated with variations in the genetic material located close to the gene that codes for the oxytocin receptor.

Along with their Austronesian culture and DNA, the Indonesians introduced their dogs» genes into populations wherever they settled.

The DNA evidence also shows that modern - day Siberian Huskies and Greenland sled dogs share an unusually large number of genes with the ancient Taimyr wolf.

BULKING UP Two beagles named Hercules (left) and Tiangou (right) are the first dogs to have a gene edited with a tool known as CRISPR / Cas9.

Although none of the German Neolithic samples carries the copy number expansion of the AMY2B gene associated with starch digestion, we find that this gene is present in three copies in NGD, though this is due to a large segmental duplication that is shared with multiple modern dogs, an event separate from the tandem AMY2B duplications.

This gene therapy drug from Xalud Therapeutics (XT - 150) has been tested in pet dogs that have chronic pain — osteoarthritis, dysplasia, neuropathic pain and disk degeneration — with remarkable results.

In the first study, the researchers have used technologies at the SNP&SEQ Technology Platform at SciLifeLab to compare genes from healthy dog individuals with genes from individuals with breast cancer.

Gene therapy shows significant progress for restoring muscle strength and prolonging lives in dogs with an incurable, inherited neuromuscular disease

Upon reflection, Dr. House notes, «Dogs with the MDR1 gene can die from certain antiparastic drugs.»

Similar to how the neck on a soda bottle restricts the amount of liquid that gets through, the frontier dogs would bring only some of their community's genes with them into a new area.

It's too soon to know just how important the genes identified in the study were in dog domestication, cautioned Ray Coppinger, during an interview with Inside Science.

On the other hand, two Italian wolves with an unusual, black coat colour did not show any genetic signatures of hybridisation, except for carrying a dog - derived variant of a gene linked to dark colouration.

On Wednesday we were saddened learned that double Nobel laureate Fred Sanger had died, so it was fitting that yesterday also saw the announcement of an important scientific advance that owes everything to the molecular biology revolution he helped to launch — one that may improve the lives of many thousands of people with Hemophilia A.... Continue reading Successful gene therapy for hemophilia A in dogs — humans next!

He and colleagues Lawrence Grossman and Derek Wildman compared approximately 10,000 protein coding genes culled from the dolphin genome with comparable genes from 9 other animals: a cow, horse, dog, mouse, human, elephant, opossum, platypus and chicken.

Researchers examined DNA data from grey wolves - the ancestors of the domestic dog — to determine how much their gene pool was diluted with the DNA of domestic canines, and how widespread the process of hybridisation is.

Analysis of the germline sequences of all the AR V genes identified greater conservation between dog and human than mouse with either.

Assessment of aortic mRNA expression for dogs with MPS I and VII, and mice with MPS VII has centered on quantification of cytokine, complement, and other inflammation - related genes [31 — 34].

The paucity of single nucleotide diversity among breeds is consistent with other studies (29 — 32) and stands in stark contrast to the abundance of coding repeat variation we found in these same genes known to be involved in the developmental processes under selection in the radiation in dog breed morphologies.

Soundstages were out, streets were in; movies with gritty urban settings like Dog Day Afternoon needed an «ethnic» actor like Al Pacino, and The French Connection a proletariat like Gene Hackman, while a host of flicks welcomed Robert Duvall.

Purpose: Many current studies are aimed at trying to identify genes associated with diseases in dogs, but we are looking to see if there might exist «protective genes» that could help protect against these same life - limiting diseases in the dog.

Recent scientific research has discovered that many dogs with two affected genes may develop the condition whereas dog with only one affected gene or with two normal genes will not.

Methods.: Dogs of various breeds, affected or unaffected with primary glaucoma, were genotyped for the Gly661Arg variant of ADAMTS10, as well as 7 other nonsynonymous single nucleotide polymorphisms (SNPs) in other genes in the beagle POAG locus that segregate with disease.

This all - stages formula offers your dog nutrition dictated by its genes and provides your pet with the kind of natural, balanced diet to be found in the wild.

This regulatory activity is genetically determined and if mutations occur in the gene or genes responsible it results in the build up of copper and a toxicosis which can occur in people with Wilson's disease and in some breeds of dogs, principally Bedlington terriers.

Occasionally it misses by a fairly large amount especially when a dog has a breed with an unknown size - influencing gene.