Sentences with phrase «dominant cause of disease»

This shift has been fueled by changes in our understanding of human biology as a result of the genomic revolution and the recognition that genes are not the dominant cause of disease.

Not exact matches

When a disease like macular degeneration is caused by a dominant gene, a number of family members may be similarly affected.

Autosomal dominant polycystic kidney disease, which is the fourth most common cause of end - stage kidney disease, requires dialysis or kidney transplant.

TSC is a multi-system autosomal dominant disease caused by loss - of - function mutations in the TSC1 or TSC2 gene.

According to geneticist James Crow of the University of Wisconsin at Madison, paternal age is the source of genetic diseases caused by new dominant mutations.

When the immune system becomes dysfunctional one of the Th1 and Th2 responses becomes dominant over the other and causing the development of chronic allergies, autoimmune diseases and recurrent infections.

The once dominant views that nicotine is not addictive, or that sodium intake is universally detrimental to one's health, or that cholesterol buildup is the primary cause of heart disease have all been rebuffed, not for lack of powerful interests working on their behalf, but because a mountain of empirical evidence discredits them.

The abundance of carriers in the population caused initial difficulties in characterizing the mode of inheritance with certainty and it was suspected that the disease had an autosomal dominant mode of inheritance.