Sentences with phrase «donor hematopoietic»

Compared with the toxicity that we see with allogeneic donor hematopoietic stem cell therapy, these toxicities are relatively manageable with close monitoring and close supportive care.
But for blood cancer patients who receive donor hematopoietic stem cell transplants as part of their treatment, graft - versus - host disease (GVHD) often hampers their recovery.

Not exact matches

Subsequently, the hematopoietic system has to be replaced with stem cells from the blood of a healthy donor.
The only curative treatment is a hematopoietic (blood - forming) stem cell transplant from a compatible donor.
Mehta J, Gordon LI, Tallman MS, et al., Does younger donor age affect the outcome of reduced - intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies beneficially?
Urgent evaluation to help identify optimal hematopoietic stem cell donor for individuals with a hematologic disorder and a family history that raises concerns
Along the way, we became interested in using cord blood as an alternative donor source for hematopoietic reconstitution after myeloablative therapy.
Isolation and characterization of mesenchymal adult bone marrow stem cells (MSC) and hematopoietic stem cells (HSC) from healthy donors and patients with leukemia.
Use of a lower dose of rabbit anti — T - lymphocyte globulin (ATLG) was superior to a higher dose in children with hematologic malignancies undergoing allogeneic hematopoietic stem cell transplantation (HSCT) from an unrelated donor, according to the results of a study published in Lancet Oncology.
University of Texas M.D. Anderson Cancer Center Tumor - specific alloantigen - anergic donor - derived T - cell therapy after hematopoietic stem - cell transplantation
Low - Dose ATLG Prevents GVHD in Pediatric Hematologic Malignancies: A newly published randomized phase III study of pediatric patients showed lower doses of rabbit anti — T - lymphocyte globulin (ATLG) was superior to a higher dose in children with hematologic malignancies undergoing allogeneic hematopoietic stem cell transplantation from an unrelated donor.
Shier LR, Schultz KR, Imren S, Regan J, Issekutz A, Sadek I, Gilman A, Panzarella T, Eaves CJ, Couban S. Differential Effects of G - CSF on Marrow and Blood - Derived Hematopoietic and Immune Cell Populations in Healthy Human Donors.
The increase in expression of donor type MHC antigens on the HPC - derived hematopoietic cells was gradual.
Previously the long - term benefits of hematopoietic stem - cell transplantation in cerebral adrenoleukodystrophy (ALD) are thought to be mediated by donor - derived replacement of myeloid derived cells, possibly including microglial cells.
Thus, one can transplant fully allogeneic hematopoietic stem cells and co-transplant, for example, hearts from the hematopoietic stem cell donor to induce lifelong donor - specific acceptance of the transplant, without deleterious immunosuppression [4].
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