«Early referral to transplant evaluation and access to information about living
donor kidney transplantation is key to a successful timely transplant and to improved long - term outcomes,» says Mark Stegall, M.D., a professor of surgery at Mayo Clinic and senior author of the manuscript.
«To help improve the gender disparities in living
donor kidney transplantation, future work is needed to learn how to support and encourage women to accept transplants,» said Dr. Gillespie.
Living
donor kidney transplantation is the treatment of choice for patients with kidney failure, but disparities exist among certain groups including blacks and women.
• After controlling for various factors known to influence transplant decisions, women were 87 % less likely to want to undergo living
donor kidney transplantation than men.
The findings, which are from a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), suggest that interventions are needed to increase women's acceptance of living
donor kidney transplantation.
• Women were less likely to want to undergo living
donor kidney transplantation compared with men (58.5 % vs 87.5 %) despite being nearly twice as likely as men to receive unsolicited offers for kidney transplants from family and friends (73.2 % vs 43.2 %).
Many programs offer living
donor kidney transplantation but require a completely compatible match.
Not exact matches
And once donation from strangers became reasonable to contemplate, it also became possible to move beyond living
donors» gifts of paired vital organs (such as a
kidney) to
transplantation of unpaired vital organs (such as the heart or liver) from cadaver
donors.
Direct - acting antiviral prophylaxis in
kidney transplantation from Hepatitis C virus - infected
donors to noninfected recipients: an open - label nonrandomized trial.
UAB's program that can make
transplantation possible between some
donors and recipients who would otherwise be incompatible, is the South's leading incompatible
kidney transplant program and the only one of its kind in the Southeast.
We're hopeful that this finding will pave the way for the future creation of
kidney tissues that could function in a patient and eliminate the need for
transplantation from a
donor.»
Their work has been avidly followed by biologists in the field of organ
transplantation: If a
donor's heart or
kidney could be frozen and stored without damage, physicians could dramatically increase the number of transplants they perform.
In more than a third of
kidney transplantations performed in the United States, the transplanted organs come from live
donors.
The study «Under - utilization of timely
kidney transplants in those with living
donors,» was published recently in the American Journal of
Transplantation.
To help provide accurate estimates of long - term risks, a team led by Dorry Segev, MD, PhD, of the Johns Hopkins University School of Medicine and the Johns Hopkins School of Public Health, studied information on 133,824 living
kidney donors from 1987 to 2015, as reported to the Organ Procurement and
Transplantation Network.
After analyzing information on 88,209
donors (176,418
kidneys), the researchers found that although the discarded
kidneys in these pairs frequently had traits that are typically considered unappealing, the partner
kidneys that shared many, if not all of the same traits performed well after being used for
transplantation despite being used in older recipients with more medical problems.
«Many
donor kidneys that are discarded may be suitable for
transplantation.»
We have also generated T - regs (CD4 + / 25high / 127low / --RRB- in vitro from
donor AD - MSC and recipient peripheral blood mononuclear cells and these T - regs are infused in thymus of renal allograft recipients after
kidney transplantation.
In some cases, organ
transplantation can be performed (e.g.,
kidney, heart, liver); however this option is typically limited by the shortage of available
donor organs.
Analysis of the sample can determine if a
kidney donor (potential live
kidney donor or deceased
kidney donor) or a patient inherited two APOL1 gene renal - risk variants that contribute to poorer renal allograft survival after
transplantation.
Freedman, Barry I., et al. «APOL1 Genotype and
Kidney Transplantation Outcomes From Deceased African American
Donors.»
Petrelli A, Tresoldi E, Mfarrej BG, Paganelli A, Spotti D, Caldara R, Secchi A, Battaglia M. Generation of
donor - specific T regulatory type 1 (Tr1) cells from patients on dialysis for cell therapy after
kidney transplantation.
My names is Dr. K. Hasti, and I am a Neurologist at MAX HEALTHCARE CENTER, Our Hospital specializes on
Kidney Surgery and we also deal on
transplantation of
kidneys with a living an corresponding
donor.