Sentences with word «dopaminergic»

It is a motor disorder caused by the loss of dopaminergic neurons in the black substance of the brain.

We also observe a significant loss of dopaminergic neurons in the substantia nigra pars compacta 60 days after infection.

Localized expression of Beta2 - containing nicotinic acetylcholine receptors in dopaminergic neurons in mice supports locomotor activating, but not rewarding effects of nicotine Yann Mineur, Yale University, New Haven, Connecticut USA

Music, an abstract stimulus, can arouse feelings of euphoria and craving, similar to tangible rewards that involve the striatal dopaminergic system.

No evidence of dopaminergic cell death was observed in DJ -1-deficient mice with the Polg mutator mutation.

«Music in the brain: The first imaging genetic study linking dopaminergic genes to music.»

Initiation of dopaminergic differentiation of Nurr1 -LRB--) mesencephalic precursor cells depends on activation of multiple mitogen - activated protein kinase pathways.

Fourthly, addiction - like effects of sugar suggest dopaminergic neurotransmission mechanisms might connect frequent sugar intake with depression23, 24,25.

Recent theoretical work by Sagvolden and his colleagues [38], however, is useful in shedding some light on how dopaminergic polymorphisms, such as DRD2 and DRD4, may lead to various forms of psychopathology.

It is not known to what extent neural and endocrine changes contribute to the increased salience of peer social status during adolescence, but it is likely that changes such as remodeling of the fronto - striatal dopaminergic systems and a puberty - linked rise in sex hormones could contribute to an increase in motivations to obtain and defend social status among peers (Nelson et al., 2005; Blakemore, 2008; Steinberg, 2008; Crone and Dahl, 2012).

Parkinson's disease (PD) is a progressive neurodegenerative disease characterised by motor and non-motor symptoms, resulting from the degeneration of nigrostriatal dopaminergic neurons and peripheral autonomic neurons.

Therefore, antiemetics that primarily block dopaminergic receptors are not expected to work the same in cats as they do in dogs.

Dr Elliott said: «The treatment of fruit flies carrying the faulty LRRK2 gene with UDCA showed a profound rescue of dopaminergic signalling.

Is there an evolutionary mismatch between the normal physiology of the human dopaminergic system and current environmental conditions in industrialized countries?

We chose to further investigate one of these drugs, amiodarone HCl, which specifically killed NSCs but not dopaminergic neurons differentiated from NSCs.

... When dopaminergic input comes in, [individuals with the SNPs on one gene copy] would have a chance of having more transmission» than those with two normal copies of the gene.

Song says one possible future use could be to grow so - called dopaminergic neurons for transplant, to replace those that die off in Parkinson's disease.

Furthermore, as dopaminergic mechanisms modulate pain responses, these researchers assessed the influence of the functional DRD2 gene polymorphism (957C > T) and the catechol - O - methyl - transferase (COMT) Val158Met polymorphism on the analgesic effect of rTMS.

The nigral dopaminergic system and the striatum, which are critically involved in action learning and motor control (as evidenced... >> MORE

Zhang W, Dallas S, Zhang D, Guo J - P, Wilson B, Miller DS, Chen B, Zhang W, McGeer PL, Hong J - S, Zhang J. Microglial PHOX and Mac - 1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha - synuclein.

Cortical dopaminergic innervation among humans, chimpanzees, and macaque monkeys: a comparative study.

Antipsychotic Drugs: Chlorpromazine Galactorrhea, Chlorprothixene, Haloperidol, Mesoridazine, Chloramphenicol, Metoclopramide, dopaminergic blocking agent, Metronidazole, Tinidazole

Dopaminergic nerve cells may in fact be especially sensitive to oxidative stress, which is why only they succumb.

Dr Miguel Martins from the MRC Toxicology Unit at the University of Leicester explained: «Parkinson's disease is a disabling disorder for which no cure is yet available; further, after dopaminergic neurons are lost, only a few palliative treatment options for Parkinson's symptoms are available.

The article, titled «Sexual dimorphism in striatal dopaminergic responses promotes monogamy in social songbirds» is a collaboration of researchers from three City University of New York (CUNY) institutions — Hunter College, the Graduate Center, and City College — as well as Weill Cornell Medicine and Houston Methodist Research Institute.

Here we use a combination of genetic and physiological approaches to identify wake - promoting dopaminergic neurons (DANs) that innervate the MB, and show that they activate wake - promoting MBONs.

The researchers believe this discovery may be potentially relevant to other neuropsychiatric disorders involving dopaminergic dysfunction (ADHD, schizophrenia and bipolar disorder) and have implications for neurodegenerative disorders that affect dopamine circuits, including Parkinson's and Huntington's disease.

Enhanced dopaminergic differentiation of human neural stem cells by synergistic effect of Bcl - xL and reduced oxygen tension

Temporally controlled modulation of FGF / ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells

It also restored dopaminergic neurons.

Large, age - related deletions in mtDNA are likely responsible for the systemic rise in oxidative stress with aging, and for localized but terrible pathologies of skeletal muscle and substantia nigra dopaminergic neurons in aging bodies.

In rats, treatment with certain dopaminergic drugs causes a disruption of PPI similar to that seen in those who have schizophrenia.

Third, whatever the level of mtDNA damage that had occurred in these animals, it was not sufficient to induce dopaminergic cell death, which again was our primary endpoint.