Houghton, L. A., Yang, J., and O'Connor, D. L. Unmetabolized folic acid and total folate concentrations in breast milk are unaffected by low -
dose folate supplements.
Not exact matches
Have not really found that
supplementing with
folate (not folic) helps, but a high
dose of TMG will lower homocysteine and in turn LDL.
Supplementing with quality brands and correct
doses of vitamins B6,
folate and B12, as well as magnesium and zinc and ensuring adequate protein intake, is essential to treating mental health conditions and mood.
[110][106] High -
dose products have received research attention, [100][111] especially for emergency situations such as vitamin A deficiency in malnutrition of children, [112] and for women taking
folate supplements to reduce the risk of breast cancer.
High
doses of folic acid from
supplements or fortified foods are of concern because synthetic folic acid is more bioavailable than
folate from natural food sources and, hence, potentially more potent in promoting cancer growth (13).
No
dose - response studies have been reported previously, and there is poor understanding of the duration of treatment necessary to produce an effect.2 - 4 Randomised controlled trials have investigated a range of
folate doses from 200 to 5,000 mcg / day with varying findings.3 - 4 Folic acid and vitamin B12 are unlikely to be an effective short - term intervention for preventing depression in
doses that can be recommended as a dietary
supplement.