A preliminary naturalistic study of low -
dose ketamine for depression and suicidal ideation in the emergency department
In small
doses ketamine is a remarkably effective antidepressant, psychiatrist Dennis Charney and a team at Yale University reported in 2000.
Not exact matches
At
doses high enough to put patients to sleep,
ketamine is an effective anesthetic.
The study randomized 20 patients with major depressive disorder to
ketamine (a single 50 mg
dose) or saline in a double - blind, crossover study.
Going forward, the Mount Sinai research team hopes to examine the mechanism of action,
dose ranging, and use functional brain imaging to further elucidate how
ketamine works.
And to Gould's surprise, the metabolite did not cause side effects in the mice even at
doses nearly 40 times higher than the antidepressant
dose of
ketamine.
When taken in low
doses (in his case, lozenges or shoulder shots) rather than drip IV,
ketamine can be therapeutic, assuaging panic attacks and softening the often constricting experiences that anxiety and depression can cause.
I encourage you to read the entire article and take note of the following: the side - effects seen with medications over the years and the fact that doctors «don't know the consequences and potential side effects of taking tiny
doses of
ketamine over and over again»; «she tried nearly everything» (you'll read this in all the articles advocating for
ketamine but unfortunately they are only referring to medications); the
ketamine effects are temporary and cost $ 15,000 per year (and are not covered by insurance); and
ketamine «is thought to stimulate an opioid receptor in the brain» and is already known to be addictive.
Respiratory depression may occur following administration of high
doses of
Ketamine Hydrochloride Injection, USP.