When the mother's and father's copies of the Igf2 gene are both mistakenly turned on, for example, the fetus gets a double
dose of growth factor.
Not exact matches
In pancreatic cancer cells, low
doses of aspirin stopped the platelets from releasing
growth factor and hampered the signaling
of the oncoproteins that cause cancer to survive and spread.
The group also tested low -
dose topical application
of growth factors on diabetic mice, which are a common model for impaired wound healing.
Publishing in Science, an EPFL group has used bioengineering to significantly improve the efficacy
of clinical
growth factors in the context
of soft tissue and bone repair, while maintaining low and safe
doses.
A group led by Jeffrey A. Hubbell at EPFL has found a way to vastly improve the efficiency
of growth factors, while keeping their usage at low
doses.
The research team, spearheaded by postdoctoral fellow Yajie Liang, Ph.D., wondered whether the cells» survival could also be enhanced with steady
doses of a compound called basic fibroblast
growth factor (bFGF), an «energy drink» that spurs cells to grow.
Differential effects
of low - and high -
dose GW2974, a dual epidermal
growth factor receptor and HER2 kinase inhibitor, on glioblastoma multiforme invasion.
Dose - dependent
growth inhibition in vivo
of PC - 3 prostate cancer with a reduction in tumoral
growth factors after therapy with GHRH antagonist MZ - J -7-138.
It appears, then, that what Dr. Campbell found was that under certain experimental conditions where high
doses of a carcinogen have been used to initiate pre-cancerous lesions, complete proteins divorced from all the natural protective
factors they are associated with in whole foods will, through their
growth - promoting properties, promote the
growth of those cancers.