Single -
dose oral administration of 100 mg caffeine increased the resting metabolic rate of both lean and postobese human volunteers by 3 — 4 % (p less than 0.02) over 150 min and improved the defective diet - induced thermogenesis observed in the postobese subjects.
Not exact matches
This led to two large clinical trials carried out by the Mayo Clinic in the late 1970s and mid-1980s (2, 3), which demonstrated that
oral administration of a high
dose of vitamin C had no efficacy as a cancer therapeutic.
The compounds have no overt effects on mood or perception, can be tolerated in high
doses, and are capable of entering the brain following
oral administration.
This protocol is a
dose escalation study of Ad - hCMV - TK and Ad - hCMV - Flt3L infused at the time of surgical resection followed by systemic
oral administration of valacyclovir in addition to current standard of care with temozolomide and radiotherapy.
«The effects of
oral administration of aqueous extract of Bulbine natalensis Baker stem at daily
doses of 25, 50, and 100mg / kg body weight on the reproductive function of Wistar rats were evaluated.»
Yes the first paper is titled «Effects of
Dosing Condition on the
Oral Bioavailability of Green Tea Catechins after Single -
Dose Administration of Polyphenon E in Healthy Individuals» and is in the June 15, 2005 issue of the journal Clinical Cancer Research.
METHODS: Electron microscopy and subcellular organelle marker enzyme studies were done in rat small intestine after
oral administration of indomethacin (
doses varied between 5 and 30 mg / kg).
Treatment most commonly involves the
oral administration of a corticosteroid, with the
dose tapered to find the lowest that controls the cough.
Injectable meloxicam (Metacam, Boehringer Ingelheim Vetmedica) has been approved for cats in the United States as a single -
dose administration.11 Daily
administration of the
oral formulation is approved in other countries, but such use remains off - label in the United States.11
A single -
dose crossover study involving 12 dogs evaluated clomipramine hydrochloride bioavailability after IV (2 mg / kg) and
oral (4 mg / kg)
administration in either a fed or fasted state.