Sentences with phrase «dose used in this study»

«Sunscreens were never meant to handle a week's worth of sun given at one time, and we are working to reduce the UVB dose we use in our studies,» she said.

The researchers did not observe any evidence of lung tumors in the urethane - treated animals seven months later, suggesting that the dose used in this study is not carcinogenic.

One 2012 study found that consuming 36 grams of protein — which was the highest dose used in the study — after a resistance training workout led to optimal levels of muscle protein synthesis, compared with doses of 10 and 20 grams.

The model of aflatoxin - dosing used in these studies, discussed in more detail below, was much more realistic than the model used in most of Campbell's studies, and thus the balance of the evidence suggests that adequate protein likely offers very powerful protection against cancer in someone who hasn't already developed the disease.

The combination of trans - resveratrol and hesperetin at the clinical doses used in the study could potentially serve as a treatment for type 2 diabetes or complement current therapies.

Given the relatively very high doses used in the study on the whole and the fact that only mild toxicity was reported, I would say that this conclusion appears to be valid but I would like to see more studies using high such high doses for comparison in order to truly validate these findings.

Moreover, the doses used in these studies (approximately 1,500 — 6,000 mcg per day) are several times higher than the iodine UL of 1,100 mcg for adults.

Not exact matches

The ENDEAVOUR Phase 3 study data monitoring committee recommended dosing be suspended after it found «an imbalance of mortality» in patients who used revusiran as compared to placebo.

«Pack - Track Seize + Adapt Case Study: Wider opportunities for a squeeze - dosing closure» uses GlobalData's Pack - Track packaging innovation tool to take a closer look at a pack format currently used in South Korea by LG Household & Healthcare for Fiji 4x Ultra Gel laundry detergent and to consider how it could potentially inspire cross-category innovation.

We used 1 mg [13C10] vitamin A [in the present study: Mretinol = retinol — H2O = m / z (mass / charge, a unit for mass spectrometry) 268, M [13C10] retinol = m / z 268 + 10 = m / z 278] in an oil capsule as a reference dose given 1 wk before the Golden Rice meal.

The University of California at San Francisco recently conducted a study where they discovered that early formula use can help women breastfeed for a greater length of time, even if doses are only in small amounts.

Although these older studies used conventional epidurals, the total dose of bupivacaine administered to the mothers (in these studies, mean doses of 61.6 mg, 93 112.7 mg, 94 and 119.8 mg, 95 respectively) was largely comparable to more recent low - dose studies (for example, 67.5 mg, 96 91.1 mg, 97 and 101.1 mg98).

In this large, population - based study, both maternal use and child's use of antibiotics were associated with an increased risk of cow's milk allergy in infancy, in a dose - related manneIn this large, population - based study, both maternal use and child's use of antibiotics were associated with an increased risk of cow's milk allergy in infancy, in a dose - related mannein infancy, in a dose - related mannein a dose - related manner.

less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)

One study found brain hemorrhages in mouse fetuses exposed to pulsed ultrasound at doses similar to those used on human babies.

The Food and Drug Administration has long permitted its use, but in recent years concerns about the chemical have grown as studies have indicated low doses of the substance can disrupt hormone systems in laboratory animals and possibly increase the risk of cancer or other serious illness.

Gaglia notes that the ferumoxytol dose used in this imaging study is approximately one quarter of the dose used therapeutically for iron replacement.

Richard Hargreaves, executive director of imaging at Merck Research Laboratories, says, «Nuclear imaging using radiotracers gives the opportunity to put your arms around proof - of - concept very early in a drug discovery and development program by focusing the selection of doses to study on those proven to deliver enough drug to the target therapeutic sites.»

The species of nosema used in the study (Nosema apis) has long been thought to be benign compared to the many other parasites and pathogens that infect honey bees, and no one had previously looked for the effect of nosema on behavior with such a low dose.

«In an earlier phase I clinical study, our group has shown that increasing the dose of radiation delivered daily with high precision and using image guidance may offset the need for chemotherapy in improving survival, and it may also improve quality of life measures by reducing treatment periods in halIn an earlier phase I clinical study, our group has shown that increasing the dose of radiation delivered daily with high precision and using image guidance may offset the need for chemotherapy in improving survival, and it may also improve quality of life measures by reducing treatment periods in halin improving survival, and it may also improve quality of life measures by reducing treatment periods in halin half.

«In the study we used drug doses equivalent to those used in the treatment of asthma patients.&raquIn the study we used drug doses equivalent to those used in the treatment of asthma patients.&raquin the treatment of asthma patients.»

«We stress that this is a proof - of - concept study in which a form of tungsten, a heavy metal that is dangerous in high doses, was used.

Now, in a provocative study that raises unsettling questions about the widespread use of vitamin supplements, Swedish researchers have showed that relatively low doses of antioxidants spur the growth of early lung tumors in cancer - prone mice, perhaps by hindering a well - known tumor suppressor gene.

About 17 percent of the parents in Yin's study used a kitchen spoon rather than a syringe, dropper or dosing cup.

Recent studies in which marijuana users took controlled doses of cannabis in the lab have identified new biomarkers that can be used to estimate a person's recent cannabinoid intake.

Study authors said about one - in - four breakthrough cases of influenza could be prevented if the high - dose vaccine were used instead of the standard - dose vaccine.

Studies in rats tend to use much higher doses of THC than even a committed pothead would absorb, and rodent adolescence is just a couple of weeks long — nothing like ours.

«The study reports asthma related emergency room visits are estimated to be 55 percent lower in people with asthma who use dose counting inhalers than in those who use inhalers without dose counters,» said allergist Allen Meadows, MD, ACAAI fellow and chair of the Public Education Committee.

The imaging software — developed and currently in use only at Cincinnati Children's — mathematically determines the lowest possible radiation dose for the patient before a scan is performed, according to the study led by David Larson, MD, radiology quality and safety director at the medical center and principal architect of the technology.

Although psychological approaches to help patients cope with pain have been used previously, what is novel in this study is the combined use of a specific psychological approach with mindfulness meditation training to help patients wean off high - doses of opioids and reduce their pain - related distress and disability.

Patients in the study were those at highest risk for developing chronic pain and persistent high - dose opioid use after major surgery.

Philip Laipis of the University of Florida, who has also observed tumors in AAV vector - treated mice, agrees, at least for studies using a similarly high dose of AAV to target liver cells, which are more likely than other cell types to take up the AAV vector.

Motivated by their previous finding of the presence of P - glycoprotein overexpression in the nasal lining of patients with CRS with nasal polyps, the study authors conducted a randomized, double - blind, placebo - controlled clinical trial studying the use of low - dose Verapamil in 18 patients with CRS with nasal polyps.

He launched the study when he discovered heart attack patients were being treated with much lower doses of beta - blockers than were used in clinical trials.

Some studies have found an increased cancer risk in mice and rats who were fed acrylamide, but those studies used doses between 1,000 and 10,000 times higher than levels that people would be exposed to in food.

Limitations of the study acknowledged include the difficulty in isolating SSRI effects from those of their indications for use, lack of information on SSRI dosage precluded dose - response analyses, and the relatively small sample of DD children resulted in imprecise estimates of association, which should be viewed with caution.

The study, which is published today in the Journal of Clinical Hypertension and is supported by Barts Charity, devised a novel treatment strategy for 55 patients, involving fractional dosing with tablets (halving or quartering pills), liquid formulations of antihypertensive drugs and patch formulations of antihypertensive drugs — plus use of unlicensed drugs that lower blood pressure.

Headline killed tadpoles in the lab at doses used on crops, according to Belden's 2010 study.

«This study draws attention to the common consensus that the use of low - dose CT scans for image guidance for children is important for quality treatment and to ensure treatment accuracy,» said Stephanie A. Terezakis, MD, co-author of the study and assistant professor of radiation oncology and molecular radiation sciences at Johns Hopkins Sidney Kimmel Comprehensive Cancer Center in Baltimore.

The investigators studied application of various doses of a common PBDE flame retardant on human adrenal cells in culture dishes and compared the effects with those of only the vehicle, the inactive substance used to deliver the chemical.

(As defined in this study, the therapeutic efficiency is 50 % of the effective dose (ED50), and is used as an index of drug strength.

However, a new study published in Cell Reports provides clues about how the dose of transplanted bone marrow might affect patients undergoing this risky procedure, frequently used to treat cancer and blood diseases.

«This study was a success in that they identified a dose of atrasentan that provided a favorable risk / benefit ratio in the patient population studied, therefore providing a dose that will be used in future studies,» they wrote.

Our study results suggest that this could be an effective wheezing prevention strategy following infant viral ARIs, however, research would first need to be done to determine the effects, adequate dosing and safety of certain antioxidant agents in infants before they can be recommended for this use.»

According to EPA, the doses used in the experiment were much higher than EPA's limits on levels to which people can be exposed, and Gray says this single study won't change regulations for vinclozolin and similar antiandrogens.

«This study supports the use of a yoga and coherent breathing intervention in major depressive disorder in people who are not on antidepressants and in those who have been on a stable dose of antidepressants and have not achieved a resolution of their symptoms,» explained corresponding author Chris Streeter, MD, associate professor of psychiatry and neurology at Boston University School of Medicine and a psychiatrist at Boston Medical Center.

A treatment group of mice were given an intake of folic acid 20 times greater than the RDA for humans: while the folic acid dosage consumed by most adults is lower and taken over a longer period of time, a higher dose was used in this study to account for the fact that mice are more efficient in metabolizing folic acid than humans.

On the basis of the current studies as well as previous reports on the use of intradermal immunization against influenza, hepatitis B, rabies, and other infectious diseases, 2,3,8 it is becoming clear that use of the intradermal route may at least partially overcome the relatively poor influenza - specific immune responses seen in certain at - risk populations, particularly the elderly, in whom the immune response in general is known to diminish with age.9 Moreover, in times of shortage, the dose - sparing intradermal approach might be particularly well suited to the young, healthy persons included in the CDC's high - priority group for vaccination, such as health care workers, as well as to younger, otherwise healthy populations in general.

The effect of glucocorticoid treatment is most prominent on trabecular bone and is therefore likely to be larger on vertebral bone than on hip bone.3 Glucocorticoids are associated with an increased rate of fracture, and higher doses and longer use of glucocorticoids are associated with higher risks of fracture.4 Compared with patients not taking glucocorticoids, the risk of hip and vertebral fracture among patients taking glucocorticoids is increased by 60 % and 160 %, respectively.4 Among 80 - year - old patients, the hip fracture risk is increased by a magnitude of 2.1 and is independent of BMD.5 Most studies indicate that fracture risk is increased following at least 3 months of treatment with daily doses of 5 mg of prednisolone or more in older men and women.4

St. Louis University researchers, through the NIAID - funded Vaccine and Treatment Evaluation Units network, will examine the optimal dose of the vaccine to be used in larger studies.