Sentences with phrase «doses of adjuvanted»

M. - P.K.: We will have 50 million doses of adjuvanted vaccine from GlaxoSmithKline.

We don't have a lot of studies to guide us how many doses of adjuvant can you give at one time in one day safely and what are the health consequences of all those adjuvants.

Not exact matches

The two schedules alternating AS03 - and MF59 - adjuvanted formulations led to lower geometric mean (average) titers (GMTs) than the group induced by two AS03 - adjuvanted formulations but higher GMTs than two doses of MF59 - adjuvanted formulation.

After 2 doses of an H7N9 formulation containing 15 µg of hemagglutinin given without adjuvant, with AS03 adjuvant, or with MF59 adjuvant, the proportion achieving an hemagglutination inhibition antibody (HIA) titer of 40 or higher was 2 percent without adjuvant (n = 94), 84 percent with AS03 adjuvant (n = 96), and 57 percent with MF59 adjuvant (n = 92).

In a phase 2 trial that included nearly 1,000 adults, the AS03 and MF59 adjuvants (a component that improves immune response of inactivated influenza vaccines) increased the immune responses to two doses of an inactivated H7N9 influenza vaccine, with AS03 - adjuvanted formulations inducing the highest amount of antibody response, according to a study in the July 21 issue of JAMA.

«Safety, immunogenicity of two doses of the HPV - 16 / 18 AS04 adjuvanted vaccine Cervarix.»

A recent study in the journal Human Vaccines & Immunotherapeutics, showed that two doses of the HPV - 16 / 18 AS04 - adjuvanted vaccine Cervarix (GlaxoSmithKline) are non-inferior to three - doses in the current schedule.

Boosting the immune response by including adjuvants, and delivering the vaccine under the skin instead of into muscle, could help to lower the dose required and cut costs, as could new kinds of vaccine, he says.

Results of EORTC trial 22921 show that compliance with adjuvant chemotherapy was poor, and only 42.9 % of the patients received the planned dose within the scheduled time frame.

Sanofi Pasteur will give a total of 100 million doses, unadjuvanted to start with, and adjuvanted later, once that is licensed.

However, scientists believe for practical use, these potential vaccines would require multiple doses or the addition of adjuvants, which enhance the immune response.

Adjuvants are increasingly used by the vaccine community and are essential components of modern vaccines, particularly for their ability to enhance and bias immune responses and for their dose - sparing properties.

Currently, lymphadenectomy is an eligibility requirement for cutting - edge adjuvant therapy trials such as Southwest Oncology Group (SWOG) 1404 (ClinicalTrials.gov identifier: NCT02506153), which randomizes stage III melanoma patients to an anti — programmed death 1 antibody or standard - of - care adjuvant therapy (high - dose interferon or high - dose ipilimumab).

Short Research Communication The Factors Reducing Relative Dose Intensity of Cisplatin and Vinorelbine as Adjuvant Chemotherapy in Patients with Non-Small Cell Lung Cancer Ryo Inose, Katsuyuki Takahashi, Naruo Yoshimura, Tomoya Kawaguchi, Mitsutaka Takada, Katsuya Nagayama Oncomedicine 2018; 3: 9 - 14.

Similar to these projects, IDRI's subunit tuberculosis vaccine, ID93, also utilizes adjuvants that induce a cell - mediated immune response, which is required for protection against M. tuberculosis infection in low dose aerosol models of TB.

Another proposed study will compare different doses of protein and a different adjuvant developed to try to induce higher and more durable antibody responses.