It's comprised
of doxylamine (an antihistamine) and pyridoxine (a form of vitamin B6).
the over-the-counter antihistamines diphenhydramine and
doxylamine are safe at recommended doses during pregnancy, even for extended periods.
Dicelgis does cause drowsiness and should not be taken if you are allergic to
doxylamine or pyridoxine, or to other antihistamines such as Benadryl or Dramamine.
Toxicology tests found marijuana, cocaine, methadone and
doxylamine, a drug found in over the counter sleep aids, in his system but the medical examiner found the substances were «noncontributory» to his death.
Researchers at St. Michael's Hospital obtained thousands of pages of documents from Health Canada relating to the randomized clinical trial that was reported in 2010 as showing pyridoxine -
doxylamine was effective in reducing nausea and vomiting in pregnancy.
Dr. Persaud said that when Duchesnay approached the FDA in the early 2000s to approve pyridoxine -
doxylamine, the regulatory agency said it needed evidence from a clinical trial.
The published results were based on 101 women who took pyridoxine -
doxylamine and a control group of 86 women; the original enrollment was higher, but many women dropped out during the trial.