Sentences with phrase «drive cell proliferation»

FOXM1 helps to drive cell proliferation, and it can promote the expression of CENP - A and PLK - 1.

Not exact matches

Chinnaiyan and colleagues then conducted studies using cancer cells and found that the different FGFR fusion proteins all seemed to drive cancer cell proliferation by activating FGFR signaling.

This drug specifically inhibits BRAFV600E, a mutated protein that drives cancer cell proliferation.

Over several years, Dr. Stewart and colleagues unraveled genes and signaling pathways that drive multiplication (proliferation) of beta cells, and then confirmed proposed mechanisms with gene therapy.

Drugs that block parts of the cell's splicing machinery may provide a new way to halt the proliferation of MYC - driven cancers.

«Role of RNA binding protein in driving cancer, leukemia study reveals: Abnormally expressed in cancer cells, the protein was found to promote the proliferation of B cells in B - cell acute lymphoblastic leukemia.»

Now researchers have discovered a new species of tRNA - derived small RNAs that are produced only in hormonally - driven breast and prostate cancers, and which contribute to cell proliferation.

It provides insights into how to transform stem cells into therapeutically useful cells and suggests possible new treatments for leukemias, in which a persistent mixed lineage seems to drive cancerous proliferation.

Chloride accumulation drives volume dynamics underlying cell proliferation and migration.

According to Sabatini, who is also a Howard Hughes Medical Institute investigator and professor of biology at MIT, this pathway is hyperactive in an estimated 50 - 80 % of cancers, driving tumor cell growth and proliferation.

Runaway cell proliferation is driven by accelerators, or oncogenes, that are stuck on go — in collusion with broken brakes, or tumor suppressors, that can't control a tumor's pedal - to - the - metal growth.

Proliferation Drives Aging - Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

CD8 (+) T cells that undergo extensive rounds of antigen - driven proliferation in cell culture invariably reach the end stage of replicative senescence, characterized by irreversible cell - cycle arrest and a critically short telomere length.

Repeated antigenic encounter drives proliferation and differentiation of memory T cell pools.

Therefore, we expected that PyMT - driven mammary tumours in Slc6a14 − / − mice would exhibit a decrease in cell proliferation, mTOR signalling and HIF1α.

IL - 7 driven T cell proliferation is refractory to most of immunosuppressive compounds.

BETHESDA, MD — Infection with Zika virus disrupts fetal brain development by interfering with the proliferation of human neural progenitor cells (hNPCs), a type of cell that drives neurodevelopment and proliferates into brain and nervous system cells, according to research presented at the American Society of Human Genetics (ASHG) 2016 Annual Meeting in Vancouver, B.C.

Toyota's comprehensive technology strategy is a portfolio approach that includes a long - term commitment to hydrogen fuel cells, plug - in hybrids and battery - electrics, all driven by the further proliferation of conventional gas - electric hybrids, like Prius as its core technology.

The proliferation of cell phone use in the past decade has leant itself to incidents of distracted driving throughout the United States.