Not exact matches
This approach, in which structure and activity is not linked to a specific protein target, can cause other difficulties and slow the progress of discovery, not least because of the difficulty of assessing relevant toxicity against host
mechanisms and the inability to use structure - guided drug -
design to
drive Medicinal Chemistry progress.
The signature feature of FOI is its commitment to the ongoing construction of theories of change that are grounded in science and
drive the
design of explicit strategies focused on specific causal
mechanisms to produce breakthrough gains on important outcomes.
Says Hirai: «Every
mechanism has been
designed for sheer
driving pleasure.
That's not a cheap solution, and as always, the final detail
design for the Camaro's
mechanism will be
driven by cost.
Having been a pioneer of automatic transmission, Teetor was already experienced with vehicle
mechanisms, so he set about
designing a solution to his lawyer's
driving habits.
Inlaid thumb beds are
designed to facilitate a dynamic
driving posture, though the form of the wheel also creates effortless access to the vehicle's distinctive paddle shift
mechanism.
We aggressively represent our clients in car accident cases including every
mechanism of injury from head on collisions, side crashes, drunk
driving accidents, rear - end crashes to defective manufacture and
design cases against auto manufacturers.