Sentences with phrase «drive tumor formation»
Two genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma (iCCA), the second most common form of liver cancer, according to a research published in the July issue of the journal Nature.
https://www.sciencedaily.com/
We then usually move onto xenograft models and then also, if available, try to test some of these compounds in genetically engineered mouse models that have particular mutations driving tumor formation.
Not exact matches
«Gene mutation drives cartilage tumor formation.»
«Treatment as it stands now is not based on the molecular abnormalities that drive brain tumor formation,» Miller said.
«Formation of a tumor is driven by genetic events,» says Dr. Roe, «but its ability to spread may not involve direct changes in the DNA sequence.»
«Formation of a tumor is driven by genetic events but its ability to spread may not involve direct changes in the DNA sequence,» says Dr. Roe.
The model will describe cellular pathways that contribute to tumor formation and explain in detail how the genetic disposition of an individual can activate expression of genes that drive uncontrolled cell growth and lead to cancer.
Our scientists understand that cancer is a complex problem involving factors intrinsic to the tumor that drive its formation, together with tumor - extrinsic mechanisms — notably the vasculature and the immune system — that enable tumor survival.
Enforced expression of miR - 200c can strongly suppress the tumor formation driven by human BCSCs and the mammary ducts formation by normal mammary stem cells in vivo, suggesting that miR - 200c is a regulator of normal mammary and BCSCs.