«Our society attributes the
weight gain and lack of exercise at mid-life (approximately 30 - 60 years) primarily to poor lifestyle choices
and lack of will power, but this study shows that there is a genetic program
driven by an overactive enzyme that promotes
weight gain and loss of exercise capacity at mid-life,» said lead study author Jay H. Chung, Ph.D., M.D., head of the Laboratory of
Obesity and Aging Research at the National Heart, Lung,
and Blood Institute (NHLBI), part of NIH.