Though this was not the case decades ago, today, most diet -
driven animal disease models are generated using open source, purified ingredient diets.
Not exact matches
Research Interests: Inflammatory bowel
disease (IBD); Crohn's
disease; ulcerative colitis;
animal models of IBD; mucosal T - cell death and survival; tolerance to gut microbiota; interactions between immune and non-immune cells; immune -
driven angiogenesis and lymphangiogenesis; intestinal fibrosis; intestinal myofibroblasts, extracellular matrix; systems biology; complex
diseases
Fallon said that in addition to the value of the findings themselves, the study demonstrates advances in creating
animal models that can be used more successfully in mimicking the
disease in ALS research, which is a key element in
driving new research and possible therapies.
•
Disease -
driving pathways that involve the human immune system are often targeted by antibodies, and Organ - Chips recreate complex interactions of different human cell types and aspects of the human immune system, overcoming limitations of
animal models which do not reflect all human immune cells.