Sentences with phrase «driven cycles with»

Mopeds: Any motor driven cycles with engines that do NOT exceed 50 cc.

Not exact matches

Along with several other analysts on Friday, including Steve Milunovich at UBS, Sacconaghi also said it was becoming clear that the latest lineup of iPhones had not sparked a massive wave of consumers with older models upgrading their phones, a prediction dubbed the «super cycle,» which had helped drive Apple's stock price up 45 % since early 2017.

«We believe expectations around the M&A cycle have become overly pessimistic and we reiterate our call for a flatter and longer M&A cycle than those seen in the past with the next leg driven by a pick - up in European and sponsor M&A as US growth slows,» Serrao writes.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

With this issue on the minds of marketers, there has been no material move by agencies to find ways to drive down production costs and improve cycle time.

You will note the Reserve Bank's rhetoric is precisely along these lines, with policy driven by common - sense and a strenuous effort to understand the cycle, rather than some doctrinal adherence to a simple rule.

Do you have what it takes to drive the full sales cycle with vendors and customers?

By: Victor Moolman 11th November 2016 South Africa is behind the global curve when it comes to the integration of mine closure and rehabilitation in the mining life cycle with the historical approach of mining companies being to focus predominantly on driving production, state consulting engineers and scientists SRK Consulting.

This skepticism about the future — even with asset prices rising — has created a negative feedback loop, driving investors to safe harbors such as cash, bonds, gold and yield - generating securities thereby reducing demand, inflation and growth in an ongoing vicious cycle.

What is more, the drive cycles of trucks and their significantly simpler routes (when compared with passenger traffic) could lead to a faster adoption of autonomous technologies on the big wheels.

After being narrowly driven by a few countries like the United States and China, we have seen the expansion broaden out, with greater participation from Europe, Japan and various emerging markets, suggesting to us that the cycle has further to run.

This is not to say that we can rule out yet higher valuations, but with no transformative technologies driving the economy, little expansion in capital investment, and ongoing retrenchment in consumer balance sheets, I can't help but think that the «virtuous cycle» rhetoric of Ben Bernanke is an awfully thin gruel by comparison.

DuPont has a proven history of driving practical, scalable solutions for sustainable packaging based on full life cycle assessment and business - driven collaboration with customers worldwide.

Plus, as may happen with other sound machines or apps on your phone, you won't be driven to the brink of insanity by the Dohm, by waiting for the loop to «click over» into the next cycle, or by waiting for that sixth whale tone or bird call, or be totally creeped out at 2 a.m. by the sound of a beating heart (oh yes, that's a sound machine option, too).

Kogi State Police Public Relation Officer, William Aya, while confirming the latest incident, said: «There was a fatal accident involving DAF Truck with REG / NO ABUJA 159 XD loaded with PMS, driven by Suleiman Yakubu, «M» of Zaria, and JINCHEN Motor Cycle with REG / NO KPA 041 ridden by Mohammed Gimba.

If Lu's suggestion is correct, ozone levels should fall then rise every 11 years, in step with changes in cosmic - ray intensity driven by the 11 - year solar cycle.

While Antarctic ice shelves are in direct contact with both the atmosphere and the surrounding oceans, and thus subject to changes in environmental conditions, they also go through repeated internally - driven cycles of growth and collapse.

So the original 6 pounds of carbon combine with 15 or 16 pounds of oxygen, minus some soot, water, and other by - products, and, bingo, by driving 21 miles down the road, my car has just disturbed the balance of the planet's carbon cycle by producing 19 pounds of CO2.

Cyclin D is synthesized during the first stage of cell replication and is believed to help drive the complex, multi-stage process, including interaction with the retinoblastoma (Rb) protein, whose function is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide.

Researchers from the Perelman School of Medicine at the University of Pennsylvania, in partnership with ORGANIZE — a non-for-profit organization based in New York which leverages health data to end the organ donor shortage by applying smarter technologies, utilizing social media, building more creative partnerships, and advocating for data - driven policies — The Bridgespan Group — a global nonprofit organization that collaborates with mission - driven leaders, organizations, and philanthropists to break cycles of poverty and dramatically improve the quality of life for those in need — and Gift of Life Donor Program — an OPO which serves the eastern half of Pennsylvania, southern New Jersey, and Delaware — evaluated the metrics and criteria used to measure OPOs across the country, and found significant discrepancies in how potential donors are evaluated and identified.

Researchers in Hawaii found that guppies released in the 1920s drove down native fish populations, perhaps by competing with them for food and living space, and had likely changed the cycle of nutrients in water: Guppy - rich areas showed increased levels of dissolved nitrogen — from ammonium in fish urine and gill excretions — which, in turn, stimulated algae growth.

One manages a household of characters, each endowed with distinct drives and personality traits, each cycling through an endless series of short - term needs (companionship, say, or food), each enmeshed in a network of relationships with other characters.

In his latest book, Musicophilia: Tales of Music and the Brain, Sacks focuses on unusual cases having to do with music's effects on the mind, such as a man who found relief from Tourette's syndrome by playing the drums, and another who was driven to the edge by an unwelcome and unending tune that cycled uncontrollably through his head.

The sediment cores used in this study cover a period when the planet went through many climate cycles driven by variations in Earth's orbit, from extreme glacial periods such as the Last Glacial Maximum about 20,000 years ago, when massive ice sheets covered the northern parts of Europe and North America, to relatively warm interglacial periods with climates more like today's.

Since changes in the soil nitrogen cycle are driven by microbes, could bacteria associated with invasive species not only be responsible for the observed changes in soil nutrient concentrations, but also for enabling the continued growth and persistence of the invader species?

With practice, car driving or cycling becomes very automatic, but there is still some interference.

At the Fuel Choices Summit in Israel this week, FCA presented the Fiat 500 M15 — a retail - ready version of the Fiat 500 that runs on a blend of 85 % gasoline and 15 % methanol; is compliant with the Euro 6 New European Driving Cycle (NEDC); delivers a 2 % CO2 reduction compared with... Read more →

It is found that the El Niño — Southern Oscillation (ENSO) is driven not only by the seasonal heating, but also by three more external periodicities (incommensurate to the annual period) associated with the ~ 18.6 - year lunar - solar nutation of the Earth rotation axis, ~ 11 - year sunspot activity cycle and the ~ 14 - month Chandler wobble in the Earth's pole motion.

Our core strengths in green chemistry and engineering research, combined with our role as a trusted third - party facilitator of stakeholder collaborations drives meaningful change toward solutions that 1) preserve natural capital, 2) are safe and sustainable across the product life cycle, 3) align and leverage different types of policy instruments, and 4) actively engage stakeholders to ensure equity.

Cyclins form complexes with cyclin - dependent kinases (CDKs), unique to each cell - cycle phase, and activate specific genes to drive cells through their cycles.

Commercial - quality 1,560 - watt countertop blender with 3 peak horsepower direct - drive motor.Preprogrammed cycles: Batters, Ice crush, smoothie, ice cream, whole Juice, hot soup

And the self - loathing keeps the cycle going, with the Shame driving the sugar bingeing underground.

With a combination of progressive overload principles, intensity driven techniques and cycling phases of hyper - volume, Max / Size will have you tossing your old clothes into the flames as you watch those old PR's go up in smoke!

These spinning bikes are built with superior geometry, a belt / chain drive system, ergonomic handles and resistant pedals that support the weight of the various user to stand and cycle.

So, you get this vicious cycle of having extra sugar in your diet to begin with, and then you were driving it higher with all of the stress hormones from all of the inflammation, right?

If you are overweight (man or woman) and / or you have any issues with your menstrual cycle, low sex drive, just to name a few — then you are at least relatively «estrogen dominant» and thus alcohol will be an even bigger issue for you.

I spend my spare time with jogging, cycling, Sometimes swimming, relaxing, motorcycle, and convertible driving, traveling and what else is so fun.

«No, his mind is not for rent / To any God or government» As the road carnage unfolds on what is revealed to be a Hot Wheels track writ large, Kaneda's light - cycle from the anime classic Akira emerges, driven by Parzival's online ally Art3mis (Olivia Cooke) and adorned with stickers for Hello Kitty, Atari, SEGA and Taito (original manufacturers of Space Invaders).

The proportion of children walking and cycling to school has been declining since 1995, with the number being driven to primary school increasing each year — as many as one in four cars on the road during the morning peak are on the school run.

Persistent claims that school districts are in fiscal jeopardy, often reported by the media, are misleading, driven by the fact that school - district budget cycles aren't synchronized with state and federal legislative appropriations processes.

The «CER - Water Cycle Labs» contains five labs for middle school students, this laboratory activities are aligned with the NGSS (MS - ESS2 - 4 Develop a model to describe the cycling of water through Earth's Systems driven by energy from the sun and the force of gravity), ready to use.

Persistent claims that school districts are in fiscal jeopardy, often reported by the media, are misleading, say the researchers, driven by the fact that school - district budget cycles aren't synchronized with state and federal legislative appropriations processes.

She uses the data cycle to drive continuous improvement with school culture.

Qualifications 7 - 10 years or more teaching experience required 2 - 3 years minimum experience as a lead / master teacher, instructional coach or head of grade - level or subject - area department required Formal management, supervisory or administrative experience required Demonstrated commitment to MWA's mission and core values Strong ability to analyze data and utilizing it to drive instruction Experience facilitating observation and feedback cycles with teachers Experience coaching or supporting teachers in Common Core standards align planning Strong organization skills and attention to detail Highly effective communication skills Ability to work effectively in a fast - paced, results focused environment Ability to laterally manage a diverse group of constituents Bachelor's Degree required; M.Ed.

Nettie Legters, Education Northwest; Douglas MacIver, Johns Hopkins University; Jason Willis, San Jose Unified School District; Emalie McGinnis, San Jose Unified School District San Jose Unified School District is scaling up its college readiness indicators system (CRIS) districtwide through a unique redesign process that links every school principal with central - office staff in routine, data - driven cycles of inquiry.

With our instructional cycles, teachers refine existing or plan new rigorous, standards - driven assignments and instruction, and assess their impact on student growth.

As we grow, Venture will remain a lean startup with the agility to try, measure, learn, and iterate in rapid data - driven cycles.

Kickboard Coaches will help you institute a powerful, yet supportive, observation and feedback cycle that uses student behavior data trends combined with rubric - based observational data to drive continuous improvement in classrooms.

Beginning January 1, 2006, street motorcycles and motor - driven cycles year model 2006 and newer, with engines less than 50 cc displacement, require an emission label certifying them to meet U.S. Environmental Protection Agency emission regulations, and may be registered regardless of mileage.

The RAV4 Hybrid uses a similar powertrain to the Toyota Camry Hybrid, combining a 2.5 - liter Atkinson - cycle four - cylinder with an electric motor, with an extra rear - mounted electric motor providing all - wheel - drive capability.