Sentences with phrase «driven immune diseases»

Not exact matches

These chemicals, called cytokines, drive the inflammation in the brain, attracting more immune cells, and causing the debilitating disease marked by loss of neurological function.

A few years ago, MS researchers were focused on a new type of immune cell called the Th - 17 cell, which appeared to be a key player in driving the neuronal damage in MS. Because Th - 17 cells produce the cytokine IL - 17, researchers likewise thought this chemical was essential to the disease.

«Oral bacteria in the gut could drive immune cell induction and inflammatory bowel disease.»

Yale University researchers have identified a handful of bacterial culprits that may drive inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis, using patients» own intestinal immune responses as a guide.

«We have long known that an activated immune system and a defective skin barrier are both important factors in eczema, but not how they are related and which one drives the disease,» said Dr. Leung.

Of note, the current study is part of a recent surge in NYU Langone findings on pancreatic cancer, including studies on how first - responder cells turn off the immune response, the role of the drug nab - paclitaxel in tumor biology, cancer cells» unique fuel sources, and how immune cell infighting drives the disease.

It was originally thought that Alzheimer's disease disturbs the brain's immune response, but this latest study adds to evidence that inflammation in the brain can in fact drive the development of the disease.

According to the authors, given the apparent differences between Western and Sub-Saharan African populations, additional studies are required to assess the basis of HIV - 1 disease in Sub-Saharan Africa as well as determine major determinants driving immune activation and inflammation in this population.

Research Interests: Inflammatory bowel disease (IBD); Crohn's disease; ulcerative colitis; animal models of IBD; mucosal T - cell death and survival; tolerance to gut microbiota; interactions between immune and non-immune cells; immune - driven angiogenesis and lymphangiogenesis; intestinal fibrosis; intestinal myofibroblasts, extracellular matrix; systems biology; complex diseases

Anna Huttenlocher, University of Wisconsin, USA Neutrophils in the Tumor Microenvironment Neutrophils, Wounds, and Cancer Progression Stefan Kaufmann, Max Planck Institute, Germany Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells Kathryn Moore, New York University, USA MicroRNA -33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis Lalita Ramakrishnan, University of Cambridge, UK Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment Beth Stevens, Harvard University, USA Microglia: Dynamic Mediators of Synapse Development and Plasticity Do glia drive synaptic and cognitive impairment in disease?

Inflammation can be a driving factor for heart disease, but in the study, low vitamin D was not linked to higher levels of inflammation markers. Additional research could determine whether those who are starting antiretroviral therapy would see better immune recovery if they took a vitamin D supplement.

«The observed increase in the ratio of cytotoxic CD4 T cells to CD4 helper T cells indicates that they are an important component of the protective immune response to viral infections and that their induction should be an important marker for successful vaccinations against certain viral diseases,» says postdoctoral researcher and first author Veena Patil, Ph.D. «But we really didn't know enough about their molecular profile and the mechanisms that drive their differentiation and maintenance.»

• Disease - driving pathways that involve the human immune system are often targeted by antibodies, and Organ - Chips recreate complex interactions of different human cell types and aspects of the human immune system, overcoming limitations of animal models which do not reflect all human immune cells.

This is an exciting finding as it suggests that the immune responses activated in at least this subset of PD patients resemble those driving autoimmune diseases like multiple sclerosis.

The integrative and functional view of Hashimoto's thyroiditis looks at some of the triggers for immune dysfunction, nutritional deficiencies, and other factors that may be causing or driving the Hashimoto's disease.

Why Inflammation Must Be Addressed at its Root... The fact that your immune system drives the inflammatory process in disease is well established.