According to a new study, published in Lab on a Chip, enzyme properties in various conditions can now be studied in multiple parallel reactions using
droplet microfluidic technology.
One area of current research is single cell manipulation and analysis using
droplet microfluidics.
Mission Bio's precision genomics platform is based on the pioneering
droplet microfluidics work of Abate and his team.
Not exact matches
Droplet - based
microfluidics is a tool used in various applications like cell cultures, chemical synthesis and DNA sequencing.
«Single - nucleus RNA sequencing,
droplet by
droplet: DroNc - Seq, technology that merges single - nucleus RNA sequencing with
microfluidics, brings new scale to gene expression studies in complex tissues.»
Chemist John Pojman of Louisiana State University in Baton Rouge adds that such roving
droplets «might be useful as a pumping mechanism for
microfluidics, converting chemical energy to mechanical motion in small devices,» such as the
microfluidic labs - on - a-chip many researchers are developing as diagnostic machines.
Working with the IIS Applied
Microfluidic Laboratory of Professor Teruo Fujii, they developed a platform to generate a myriad of micrometer - sized
droplets containing random concentrations of reagents and then sandwich a single layer of them between glass slides.
In the past 10 years, other research groups have experimented with «digital
microfluidics,» or electrical manipulation of
droplets, to conduct biological experiments.
A recent paper in the Proceedings of the National Academy of Sciences (PNAS) describes how researchers at KTH / SciLifeLab were able to find more productive yeast and the underlying genetic alterations using picoliter
droplet screening in a
microfluidic system.
With his Pioneer Award, Ismagilov will develop
droplet - based
microfluidic technologies for quantitative studies of protein aggregation diseases and aging at the molecular level and in entire organisms.
Researchers at SciLifeLab have shown that a high - throughput method using
microfluidic droplet sorting of mutated yeast cells can be used to improve the production of industrial enzymes.
As part of his post-doctoral research at University of Chicago he co-invented the SlipChip - a multiplexed
microfluidic platform for high - throughput
droplet - based chemistry and biochemistry without pumps or valves.