Sentences with phrase «drug candidate called»

When they treated mice modeling HER2 - positive breast cancer with a drug candidate called MSI - 1436 (also called trodusquemine), Tonks and colleagues not only inhibited signaling by PTP1B, but also signaling by HER2 proteins.

Several years ago, for example, poor chemical probe data led researchers to pursue a final stage clinical trial on a cancer drug candidate called iniparib.

Not exact matches

Merck is the latest company to weather bad news in the Alzheimer's drug race, halting a late - stage trial yesterday in an experimental amyloid - targeting candidate called verubecestat after a data monitoring committee said there was «virtually no chance of finding a positive clinical effect,» Reuters reported.

That's particularly unfortuante for Cerecor seeing as CERC - 501 is the company's lead drug candidate — and the news comes just days after Cerecor announced that a separate experimental depression drug called CERC - 301 had also failed in the clinic.

During Thursday's call, Goldman Sachs (gs) analyst Jami Rubin pressed Frazier on the possibility of upcoming deals, including the type of investigational drug candidates and companies that Merck may be interested in purchasing.

Biotech stocks slumped Tuesday ahead of the Democratic presidential debate on speculation that candidates will call for measures to limit drug - price increases.

Hawkins Calls for Truth and Justice Commission re Mass Incarceration (Albany, NY) Howie Hawkins, the Green Party candidate for Governor, called for an end to the war on drugs and the establishment of a Truth, Justice and Reconciliation Commission to address the impact of mass incarceration on people of color.

Gov. Andrew Cuomo today dismissed Republican presidential candidate — and fellow Queens native — Donald Trump «s calls for a wall along the Mexican border to prevent rapists and drug - dealers from flooding the country as «offensive and low,» and contrary to New York's immigrant history.

Democratic gubernatorial candidate Cynthia Nixon on Wednesday in a video called for the legalization of marijuana in New York, a move she said would end a racist drug policy that disproportionately impacts black and Hispanic people.

«Yet here we are in 2015 and a leading candidate for the GOP nomination for president is calling Mexicans criminals, rapists and drug dealers,» the letter states.

Howie Hawkins, the Green Party candidate for Governor, called for an end to the war on drugs and the establishment of a Truth, Justice and Reconciliation Commission to address the impact of mass incarceration on people of color.

Public Advocate Letitia James, a rumored 2021 mayoral candidate, is calling for the legalization of marijuana for adult recreational use in New York State amid a nationwide movement pushing for legalization and renewed attention around racial disparities in drug - related arrests.

The Drug Policy Alliance, a nonprofit focused on ending the so - called war on drugs, is funded by billionaire George Soros and does not endorse candidates.

The drug candidate, called mavoglurant, had shown promise in mice with a genetic condition similar to fragile X. The...

The drug candidate, called mavoglurant, had shown promise in mice with a genetic condition similar to fragile X...

Then his group got a drug candidate ready for the clinic, and he was reshuffled into a safety and pharmacology role — «a recipe for disaster,» he calls it.

Two years ago the pharmaceutical giant GlaxoSmithKline purchased Sirtris for $ 720 million, and by August of last year The New York Times was speculating that compounds capable of activating sirtuin genes were now the leading candidates for what the newspaper called «the ultimate free lunch... a drug that tricks the body into thinking it is on [a calorie - restricted] diet.»

His team looked at an experimental drug called PTC124, which the firefly luciferase assay had identified as a promising candidate for treating stop - sign forms of cystic fibrosis and which is now being tested in clinical trials.

Triple - negative cancers are so called because they do not express receptors for the hormones estrogen and progesterone, nor for HER2 (human epidermal growth factor 2), and hence patients with these cancers are not candidates for treatment with modern hormonal therapies or the highly effective HER2 - targeted drug Herceptin (trastuzumab).

The new process, called Extensive Combinatorial Refinement (ExCoR), could help improve the development of drug candidates that depend to a great degree on detailed structural analysis to determine how they work against specific disease targets.

«The goal of the deCODE collaboration was to generate a final optimized compound with the required properties of an effective SMA drug, called a «Clinical Candidate».