Sentences with phrase «drug cisplatin»

This is the first time that an Osmium - based compound — which is fifty times more active than the current cancer drug cisplatin — has been seen to target the disease.

One of these, UJ3, is as effective as the industry - standard drug Cisplatin in killing cancer cells in laboratory tests done on human esophageal cancer, breast cancer and melanoma.

In early studies on rabbits, the anticancer drug cisplatin, a simple but highly toxic chemical containing platinum, was added to Intradose CDDP.

Dartmouth researchers previously demonstrated that STK17A is a protein that is induced when DNA is damaged by the chemotherapeutic drug cisplatin.

• Platinum - Resistant — these are patients whose disease recurred within six months of conventional chemotherapy (using the drugs cisplatin or carboplatin) and are generally less responsive to subsequent treatments and have not responded as well to PARP inhibitors.

Not exact matches

Some very significant medical discoveries were made by accident — penicillin, cisplatin (a chemotherapeutic drug), and even Viagra.

The research involved engineering nanostructures containing both gold and cisplatin, a conventional chemotherapy drug.

A team of researchers led by Dr. Jian Zuo screened over 4,000 drugs for their ability to protect cochlear cells from the chemotherapy agent cisplatin.

Thirty minutes after injecting the gel and cisplatin into the tumours, the levels of cisplatin were five times higher inside the tumour than when the drug was injected without the gel.

The researchers showed how gelsolin works at the molecular level to protect cancer cells against a widely used chemotherapy drug called cisplatin.

They used this method first in 2015 to generate a UV repair map of the human genome, and in 2016 they used the XR - seq method to generate the damage and repair maps of the anticancer cisplatin drug for the entire human genome.

In the Cancer Cell article, the researchers describe how various anticancer drugs, including cisplatin and the targeted therapy vemurafenib, which targets melanomas with the BRAF mutation, become more effective when co-delivered with phenformin.

They found that adaptive immunity is reversely associated with resistance of cisplatin, the drug used for ovarian cancer.

Cisplatin and cyclophosphamide were the other drugs used in this study.

The history of cisplatin, the drug that is still the gold — or should that be platinum?

Aerosol administration was performed as follows, the residual cup was filled with 8mls of the cisplatin agent and the nebulisation time was 10 minutes (almost 1 ml / minute) as observed from our previous studies.14 The aerosol was delivered to the mice (one by one) within a nose only cage that has been previously presented.34 In the groups receiving the intratumoral cisplatin an insulin injection was used to deliver the 2mls of cisplatin within the tumor in different depths, however; a quantity of the drug when the injection was made superficially was lost since it was not accumulated.

The chemotherapy drug was obtained from our Lung Cancer Oncology Unit; i) Cisplatin / Hospira ® 100mg / ml ONCO - TAINTM.

The first relies on the biochemical properties of a drug, while the second uses the antigen / antibody connection.26 The use of biotynilated - epidermal growth factor (EGFR) has been used to enhance the accumulation of cisplatin.27 Other local factors in the respiratory system influencing the absorption are the local transporters and genes.

The structure of these transporters is essential to the rational design of agents which control their function.30 - 32 In our current work we investigated the chemotherapy agent cisplatin since it the most used chemotherapy drug for a number of cancer types and the application would have an impact on several cancers.

8/27/2008 Variation of Normal Protein Could Be Key to Resistance to Common Cancer Drug Researchers at the Moores Cancer Center at the University of California, San Diego (UC SD) in La Jolla have found evidence explaining why a common chemotherapy drug, cisplatin, may not always work for every cancer patiDrug Researchers at the Moores Cancer Center at the University of California, San Diego (UC SD) in La Jolla have found evidence explaining why a common chemotherapy drug, cisplatin, may not always work for every cancer patidrug, cisplatin, may not always work for every cancer patient.

MIT's new nanoparticle carries three cancer - fighting drug molecules — doxorubicin is red, the small green particles are camptothecin, and the larger green core contains cisplatin (Image: Jeremiah Johnson)

The team has tested its triple threat nanoparticles, containing drugs typically used to treat ovarian cancer (such as doxorubicin, cisplatin and camptothecin), against lab - grown ovarian cancer cells.

It happened while I was undergoing my first round of a chemotherapy — a combination of drugs called R - DHAP (rituximab, dexamethasone, cytarabine and cisplatin).

In addition, the drug of choice was cisplatin, which can sometimes cause deafness.

These include anti-seizure drugs like gabapentin, chemotherapy drugs like docetaxel and cisplatin, and medications to treat Parkinson's Disease like Mirapex (pramipexole) and Requip (ropinirole).

This drug is indicated in combination with Cisplatin (a chemotherapeutic drug) for the first - line treatment of patients with inoperable, locally advanced, or metastatic non-small cell lung cancer.

FDA on chemo beads Cisplatin beads have not been approved by the Food and Drug Administration (FDA) for use in cats.

Cisplatin is a common chemo drug, normally used with an IV in our canine cancer patients.

Medications: Some drugs, such as organophosphates (in older generation garden products), azathioprine, potassium bromide, L - asparaginase, cisplatin and thiazide diuretics, have been linked to pancreatitis.

Commonly used drugs are adriamycin, vincristine, cytoxan and cisplatin.

The most successful drugs have been carboplatin and cisplatin.

CISPLATIN (Platinol) Nausea and vomiting — usually only seen during administration of the drug or within first 24 - 48 hours, often controlled with medication.

The drugs administered are cisplatin, carboplatin, or doxorubicin.

The treatment results are almost identical for the 3 drugs; because cisplatin has to be given as an IV infusion, most oncologists are no longer using it.

We currently recommend to use a combination of 2 different drugs: Adriamycin (doxorubicin) and cisplatin or carboplatin.