Sentences with phrase «drug design»

This finding suggests new targets for drugs designed to treat inflammatory diseases.

A new study finds that rising placebo responses may play a part in the increasingly high failure rate for clinical trials of drugs designed to control chronic pain caused by nerve damage.

In drug design, for example, the function of a protein is determined by sequence comparison and 3D modelling programs.

These will serve as starting points for structure - based drug design projects.

We're now testing new drugs designed to target and kill the cancer stem cells.

These brave volunteers are the first HD patients to ever be treated with drugs designed to attack HD at its root cause, a treatment approach with huge potential.

This could open the door for novel drug designs, they say.

What's more, simulations are useful for structure - based, computer - aided drug design.

These new findings could aid future drug design by giving scientists an edge in fine tuning the signal between these partnered proteins — and the drug's course of action.

Men with aggressive prostate cancer that has stopped responding to conventional treatment could potentially benefit from a new class of cancer drug designed to overcome drug resistance, a new study suggests.

And for the first time, researchers are testing an experimental drug designed specifically for postpartum depression.

However, there are also clinical studies on drugs designed to kill the mites.

The new data come at a time when clinical trials have repeatedly tested drugs designed to raise HDL cholesterol, only to have them fail to make improvements in heart disease.

But there's a dark side to cancer - killing drugs designed to match distinct cancer mutations like a key into a lock.

And drug delivery, much like drug design, is an immensely complex task.

• This knowledge, which is available to the scientific community, may be of great use to minimize and predict adverse effects during drug design.

By uncovering the precise cellular mechanisms of nicotine's effect, this study suggests new and more precise targets for drugs designed to block this powerful craving.

The study could help identify people who would most benefit from new drugs designed to save brain cells, but more research is necessary to determine if the genetic mutations are implicated in disease.

On the other hand, first clinical trials with drugs designed to target cancer stem cells are now under way, so far yielding moderately positive results.

That's a dismal failure rate for a class of drugs designed to improve a person's basic ability to function.

He moved to the National Cancer Institute in 1992 for a post-doctoral fellowship and became interested in rational drug design, a relatively new concept at the time, but one that fit Buolamwini's needs.

The findings also have the potential to guide drug design for pain, inflammation, obesity, fibrosis and other indications.

«Everybody else (developing drug design strategies) had been thinking they had to go after all the Ras mutants,» Shokat says.

«Structural Discoveries Could Aid in Better Drug Design.»

Adams underscores that the ability to understand the configuration of atoms in molecular space can be used to generate new insights into drug design and development.

Chemogenomics is a new concept where drug design and screening is conducted at the genome level for selective drug discovery effort against one target among a large family of related proteins / receptors.

Scientists have developed a three - in - one blood test that could transform treatment of advanced prostate cancer through use of precision drugs designed to target mutations in the BRCA genes.

Disrupting this centrally positioned protein could «throw a wrench» into the middle of the efflux pump and mechanically break it, unlike drug design strategies that try to inhibit overall biochemical processes.

«They also provide a promising strategy for identifying small molecule drugs designed to treat Alzheimer's disease and other neurological disorders.»

Now, new images published in Nature Communications provide snapshots of the receptors, including details about molecular binding sites that could lead to more precise drug design.

An exciting development in rational anticancer drug design is Gleevac, a drug that acts on a protein unique to the defective white blood cells in chronic myelogenous leukemia and on a related protein in a rare form of gastrointestinal cancer.

A multi-institutional project to understand one of the major targets of human drug design has produced new insights into how structural communication works in a cell component called a G protein - coupled receptor (GPCRs),...

The investigation has exposed the crucial role of pharmacists and doctors in creating and prescribing programmes of performance - enhancing drugs designed to cheat the testing system.

How about the antibacterial drugs designed to the kill the bacteria and viruses the livestock carry from as a result of eating GMO food?

Student Research Helps Discover Cancer Drugs Cancer drug design provided a challenging PhD dissertation topic for Almut Mecke, a physics student at University of Michigan.

It was the first drug designed to inhibit new vessel growth (angiogenesis), and was approved by the FDA in 2004 for treating colorectal cancers — which typically boost angiogenesis to keep themselves well supplied with oxygen and nutrients.

Apart from intriguing methodological and biological insights, the results have important implications for human health, as it provide a reference for analysis of mutations that cause severe pathologies and for future drug design.

Prior to that he was CEO of Molecular Simulations, Inc., a $ 100 MM supplier of software for drug design now called Accelrys (NASDAQ: ACCL).

In the history of drug marketing, the single most successful drug to ever hit the market was a drug targeted at seniors: Lipitor, the statin drug designed to lower cholesterol levels.

Episiotomy rates are low, the increased c - section rate corresponds with better outcomes and isn't as high as you think, and pitocin is a useful medication with legitimate indications, not some horror drug designed by OBs to ruin women's experiences.

In 2008, Novartis supported their joint work on chemotherapy delivery agents with its Pharmaceutical and Medicinal Chemistry Drug Design and Development Research Award.

Over the past 5 years, a few promising candidate drugs designed to ward off the effects of radiation exposure have begun to undergo animal, and even human, testing.

Chemotherapy drugs designed to kill tumors may actually encourage ovarian cancer by stimulating the growth of cells that give rise to the malignancy, a new study finds.

He said the study shed light on the specific mechanism by which the dengue virus enters cells, and could help explain why some vaccines may not work, while providing a basis for dengue drug design.

Multi-scale QM / MM computational methods are crucial to advancing the understanding and solution to problems in the chemical sciences, ranging from drug design to renewable energies.

Today Brain publishes a new study indicating that antiepileptic drugs designed to reduce seizures, may also induce psychotic disorders in some patients.

Today it announced that a CRC - funded professor will move his gene - targeted drug design research group from the university.

Unlike most existing drugs designed to suppress appetite, which operate on receptors in the brain, enterostatin is formed in the gut and appears to regulate the craving for fat.

Graduating students might find employment in, for example, academia, national research laboratories, pharmaceuticals, industrial drug design, manufacturing and automotive, medical / health professions such as bioinformatics.