Prior to that he was CEO of Molecular Simulations, Inc., a $ 100 MM supplier of software for
drug design now called Accelrys (NASDAQ: ACCL).
Not exact matches
Drugs that were effective at warding off infections decades ago are
now less potent because the bacteria they were
designed to kill have developed defence mechanisms.
In a 1992 article in The North American Review entitled «The Corruption of Nobility: The Rise & Fall of Thoroughbred Racing in America,» Ferraro penned a stinging rebuke against
drug abuse on the backstretch, saying, «In general, treatments
designed to repair a horse's injuries and to alleviate its suffering are
now often used to get the animal out onto the track to compete — to force the animal, like some punch - drunk fighter, to make just one more round.
Now that researchers know from their cell studies that this family of receptors can essentially flip its own switch, they can use that information to
design drugs to prevent that from happening when it shouldn't.
She says a number of experimental
drugs now in clinical trials are
designed to target serotonin in other ways in the brain, and may have better success than the SSRIs.
«Our computer aided
drug screening process has
now identified two new classes of anti-cancer agents, specifically targeting two distinct and novel mechanisms underpinning cancer,» said Dr Andrea Brancale from Cardiff University's School of Pharmacy, who led on the compound's
design.
«
Now the challenge is to
design experimental studies using biomarkers in cognitively normal people to determine who can really benefit from the
drugs.»
Ad agencies are
now in a position to help
design studies so that the results will create the best possible marketing opportunities for the
drug companies.
Learning more about the new strains could help public health officials to determine which
drugs might be effective and to
design new vaccines for the next flu season, which will likely include strains that are
now circulating.
«
Now, because we know the resistance mechanism, we can
design elements to minimize the emergence of resistance as these promising new
drug candidates are developed,» said Ben Shen, a TSRI professor who led the study, which was published February 20, 2014 online ahead of print by the Cell Press journal Chemistry & Biology.
DeCode is
now negotiating with some of the world's largest pharmaceuticals companies, which hope to use deCode's genetic insights to
design new
drugs.
A race is
now on to commercialize quantum computers, making them available to companies that want to solve problems particularly suited to quantum machines, such as
designing new materials or speeding up the search for new
drugs.
Professor Michael Lisanti, who
designed the study, explained: «We
now know that a proportion of cancer cells escape chemotherapy and develop
drug resistance; we established this new strategy to find out how they do it.
Determining the similarities of molecular structures
now plays an important role in
designing all kinds of new molecules — mainly
drugs, but also pesticides, fuels, polymers and substitutes for blood and other body fluids.
Now the precise structure of the pyripyropenes is known, chemists should be able to
design similar molecules that may be even more effective at blocking ACAT and form the basis of
drugs to treat atherosclerosis.
Now researchers have identified a protein that may be a good target for
designing drugs to improve the stability and strength of broken bones.
Until
now, agents that inhibit Pin1 have been developed mainly through rational
drug design.
Drugs originally
designed to treat mental disorders are
now being taken by perfectly healthy people.
On the other hand, first clinical trials with
drugs designed to target cancer stem cells are
now under way, so far yielding moderately positive results.
It is
now possible to
design drugs that go right to the vulnerable target of a disorder, thanks to the research produced from the Human Genome Project.
We're
now testing new
drugs designed to target and kill the cancer stem cells.
Now that we understand why, we can
design better
drugs to combat cystic fibrosis in humans.»
Children as young as 18 months are
now receiving antipsychotic
drugs, despite the fact that the diseases they're
designed to treat rarely develop before adolescence.
They're
designing drugs now that are blocking mTOR, and they define it as molecule that helps drive the growth of many tumors.
Now, the justices are trying to decide whether generic
drug manufacturers can be sued in state court for
design defects - especially when the generic version is an exact copy of its brand - name counterpart that the federal government had already approved.
I've followed Sarah's charming blog, Flourish
Design and Style for years
now (it was the gateway
drug of Canadian blogs for me!)