Sentences with phrase «drug design research»

Today it announced that a CRC - funded professor will move his gene - targeted drug design research group from the university.

Not exact matches

That cash doesn't include the money PhRMA's spending on the ongoing «Go Boldly» campaign, a series of TV, print and radio ads designed to polish the drug industry's image by reminding the public that drug companies do world - class research that brings disease cures to market to save lives.

«We could apply the strategy used in this study to quickly identify and design small molecule drugs for other RNA - associated diseases,» explained study first author Sai Velagapudi, a research associate in the Disney lab.

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have designed two new drug candidates to target prostate and triple negative breast cancers.

Randolph Nesse and Kent Berridge, psychiatric investigators with the Institute for Social Research at the University of Michigan in Ann Arbor, reported in Science that medicine may never win the war against drug addiction because «it is rooted in the fundamental design of the human nervous system.»

«This well - designed set of experiments shows that chronic THC pretreatment appears to restore a significant level of diminished cognitive performance in older mice, while corroborating the opposite effect among young mice,» wrote Susan Weiss, director of the Division of Extramural Research at the National Institute on Drug Abuse, who was not involved in the study, in an e-mail.

Student Research Helps Discover Cancer Drugs Cancer drug design provided a challenging PhD dissertation topic for Almut Mecke, a physics student at University of Michigan.

Video of Eve, which can apply the same automated cycles of research to drug screening and design, albeit in a much more elegant fashion.

The research team currently is working to identify new biomarkers that will allow them to develop a better understanding of how drug resistance develops, and how to best design effective combinations of medications that may improve patient responses.

Researchers at the Pharmacy Department of the CEU Cardenal Herrera University have published the design of a new bioadhesive ocular insert which is placed inside the eyelid and releases a larger amount of medicine through the cornea in a controlled way in the international journal Drug Delivery and Translational Research.

To measure risky online self - presentation the research team, which also included PhD student Clara Cutello, Dr Michaela Gummerum and Professor Yaniv Hanoch from the School of Psychology, designed a risk exposure scale relating to potentially inappropriate images or texts, such as drug and alcohol use, sexual content, personal information, and offensive material.

Much research is trying to design drug molecules able to cross such barriers, which can act as very specific filters.

As Cournia contemplated returning to her home nation, she researched how her subfield of computer - aided drug design would fit in with the strategic initiatives of Greek institutions.

The research explains how tumors evolve and cause cancer resistance to drugs designed to match the patient's unique genomic makeup.

The research could lead to better designed drugs.

His multidisciplinary academic research spans computer modeling, protein - protein / protein - ligand structural analyses, drug design, and synthetic medicinal chemistry, incorporating the principles of chemogenomics.

Professor Davis, author of the popular Penguin paperback The Compatibility Gene, concludes: «The practical application of this basic research comes from bouncing around our ideas with scientists working on drug design.

In this collaboration, Dickerson designed the synthesis of drugs from precursor compounds prior to scheduling, when they are not available from research supply companies.

A molecule in cells that shuts down the expression of genes might be a promising target for new drugs designed to treat the most frequent and lethal form of brain cancer, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).

The discovery involved ORNL's Spallation Neutron Source, which provides the most intense pulsed neutron beams in the world for scientific research and industrial development, and ORNL's Titan supercomputer, the nation's most powerful for open science — a one - two punch for illuminating the physical properties of potential drugs that inform new design principles for safer, improved delivery platforms.

Graduating students might find employment in, for example, academia, national research laboratories, pharmaceuticals, industrial drug design, manufacturing and automotive, medical / health professions such as bioinformatics.

Professor Elkington highlights that more research is needed to investigate the hypothesis but if it is proved, the discovery could have major implications for the design of new vaccines and drug treatments.

Consequently, many research groups are in hot pursuit of finding new drug targets and designing novel ones against the disease.

The molecular details of our discovery will facilitate the design of new drugs and new vaccines,» said Alexis Kaushansky, PhD, an assistant professor at the Center for Infectious Disease Research.

Burdick's team and other research groups are also designing hydrogels that contain drugs or cells that can repair heart tissue.

This research on these protein clusters, or aggregates as scientists call them, could help guide design of new anticancer drugs.

Cosa's research group specializes in single - molecule fluorescence techniques, while Sleiman's uses DNA chemistry to design new materials for drug delivery and diagnostic tools.

Once they identified the function of the protein, Moore's research team was able to design a biologic drug that can prevent the messenger RNA gene from creating HE4.

The study could help identify people who would most benefit from new drugs designed to save brain cells, but more research is necessary to determine if the genetic mutations are implicated in disease.

Gerry Potter and Ray McCague of the Institute of Cancer Research in Surrey based their design strategy on tamoxifen, a drug widely used for treating breast cancer.

An aim of future research will be to design enzymes in a computer to, for example, produce new drugs.

In recent research published in the Journal of Biological Chemistry, Saint Louis University investigators report catching integrase, the part of retroviruses like HIV that is responsible for insertion of the viral DNA into human cell DNA, in the presence of a drug designed to thwart it.

As the pace of drug approvals accelerates and the U.S. Food and Drug Administration (FDA) faces potential budget cuts, a new research design from Perelman School of Medicine scientists offers a new way to successfully assess safety of newly approved drugs, as well as drugs that have been on the market for a long time and have had a marked rise in their drug approvals accelerates and the U.S. Food and Drug Administration (FDA) faces potential budget cuts, a new research design from Perelman School of Medicine scientists offers a new way to successfully assess safety of newly approved drugs, as well as drugs that have been on the market for a long time and have had a marked rise in their Drug Administration (FDA) faces potential budget cuts, a new research design from Perelman School of Medicine scientists offers a new way to successfully assess safety of newly approved drugs, as well as drugs that have been on the market for a long time and have had a marked rise in their use.

In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time designed a drug candidate that decreases the growth of tumor cells in animal models in one of the hardest to treat cancers — triple negative breast cancer.

The experimental research, conducted by Griffith University's Centre for Quantum Dynamics, aims to help in the design of new molecules for materials science or drug discovery.

By explaining how the drug operates, their research might allow others to design new antibiotics that could in fact be used to treat tuberculosis patients — and might even work on other bugs.

«Furthermore there are other options such as specially designed spectacle lenses and contact lenses or drug interventions but increased investment in research is needed to improve the efficacy and access of such interventions.»

Dr Emma Smith, senior science communications officer at Cancer Research UK, said: «Revealing the molecule's detailed shape could be the first step towards designing more precise drugs to block it.

The research could help other scientists to use cryo - EM in structure - based drug design studies — in which researchers build the best possible drugs starting from a molecule which already binds to the active site of a target protein.

In 2015, Forbes reported that Yancopoulos became the first pharmaceutical research chief to become a billionaire, as a result of his work at Regeneron, which includes inventing four approved drugs and designing the technology to assist in making more.

The findings open up new avenues of research into exactly how the brain controls eating, and suggest that drugs designed to activate or inhibit neurons in the DRN could be effective in treating obesity and preventing its related disorders, such as diabetes and hypertension.

«FDA's approach to evaluation of recent hepatitis C drugs underscores the Agency's flexibility in considering innovative or alternative trial designs for drugs that have demonstrated highly promising outcomes in early phase development,» said Dr. Poonam Mishra, deputy director for Safety, Division of Antiviral Products / Office of Antimicrobial Products in the FDA's Center for Drug Evaluation and Research and lead author of the Hepatology paper.

You are involved in pioneering projects, designing new and innovative approaches to drug development,» says Rainer Constien, a molecular biologist and former research scientist at Munich - based Ingenium Pharmaceuticals AG.

UNC scientists led by John Sondek, PhD, created a new biochemical tool to block specific types of downstream G - protein signaling, opening new avenues of research and potential drug design and discovery.

Janssen GPH will also prioritise work with the International Partnership for Microbicides developing the investigational drug dapivirine for use as a monthly vaginal microbicidal ring designed to prevent sexual transmission of HIV and continue its pact with Drugs for Neglected Diseases initiative for the preclinical research of a reformulated form of flubendazole for lymphatic filariasis (elephantiasis) and onchocerciasis (river blindness), Janssen GPH is also developing a new, chewable formulation of Vermox (mebendazole) that will facilitate treatment of intestinal worms in younger children.

At the LACDR we work at the leading edge of drug - design and fundamental research of new drugs, optimisation of existing drugs, and personalised medicine.

WASHINGTON, DC — May 16, 2010 — At a time when the cost of developing a new drug is skyrocketing and research money is tight, it is important to be creative in designing new therapies for rare diseases and bringing them to market, according to speakers at the eighth Annual Meeting of the American Society for -LSB-...]

The meeting explored the genomic epidemiology of the host, vector and parasite, highlighting the practical relevance of this research to global health, including antimalarial drug resistance, insecticide resistance, vaccine design, and mechanisms of protective immunity.

I got a new laboratory of research in bioinformatics and computational chemistry, in which we develop mostly studies in drug design and in silico evaluation of environmental pollutants, and I also proposed a new master program in Bioinformatics.

With an over $ 70 million commitment over multiple years from the NIH and the Wellcome Trust, H3Africa is designed to create and support a pan-continental network of labs that will be equipped to apply leading - edge research to the study of the genetic and environmental basis of disease susceptibility and drug responses in Africans.