Sentences with phrase «drug development through»
Our team of experienced trial and appellate lawyers craft and execute comprehensive intellectual property strategies from initial drug development through trial and appeal.
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To assist drug development through the identification of essential genes and pathways, we have measured competitive growth rates in mice of 2,578 barcoded Plasmodium berghei knockout mutants, representing > 50 % of the genome, and created a phenotype database.
The investigations include research on protein crystal growth, which may lead to drug development through protein mapping, and plant biology.
Not exact matches
Zymeworks, meanwhile, went through a number of lean years; investors in Canada were still more comfortable with a development model that produced widely applicable chemical drugs.
Alnylam $ ALNY may be going solo on the development of rare disease drug lumasiran after Sanofi took a pass on its option, but the FDA has come through with a major assist.
Sierra Oncology, Inc., a clinical stage drug development company focused on advancing next - generation DNA damage response therapeutics for the treatment of patients with cancer, went public near $ 29 in July 2015, then began a downtrend that continued through a June 2017 all - time low of $ 1.10.
UCSD's renowned Cancer Therapeutics Training Program, also known as CT2, addresses the shortage of professionals qualified to oversee the development of innovative, new cancer drugs through its two - year intensive post-doctoral student training at National Cancer Institute - designated Comprehensive Cancer Centers.
Educational Session # 1: When: June 3rd, Wednesday, 3:15 PM — 4:00 PM Where: Institute 2015 Pre-conference Cybersecurity, Technology and Infrastructure Advancements Forum What: Optimize PBM Value Proposition to Payers through Disruptive Innovation by Terry Ramey, EVP, Business Development and Client Engagement Session Details: PBMs that manage over $ 300 billion of pharmacy benefits for plan sponsors have historically been challenged to support plan sponsors» goals to reduce avoidable drug - impacted medical costs and optimize overall pharmacy costs.
A spinoff or sale could benefit Pfizer through additional cash that it could use to acquire new high - growth products that are already approved or are late in the drug development process.
By accelerating promising drug candidates through the drug discovery and development pipeline and spearheading innovative public - private partnerships, we increase the chance of finding an effective treatment, and a cure, for Alzheimer's disease.
Smoking and drug use — smoking through pregnancy can affect your baby's development in a number of ways and increases your chances of having a premature baby
The funding is provided through the State's Public Housing Modernization Drug Elimination program, part of a modernization program that provides grants to public housing developments where rental income is insufficient and funds are unavailable from other sources for needed repairs and improvements.
«When the AIDS crisis burned and ravaged its way through this community and thousands of gay men were literally dying, every day New Yorkers stood up... they organized, they put their bodies on the line... they forced the development of antiretroviral drugs and that's why me and many people are alive today.»
Although these postdocs are active in research, the talk largely centered on moving scientific advances through the complex drug - development process to the marketplace and the clinic — and on the skills and strategies needed to build a career in industry.
The Cent - 1 molecule kills cancer cells through a mechanism similar to that of the template drug Rigosertib that is currently under commercial development.
What I especially like about working for UKHTB is that it offers a new challenge and is pioneering in an area that has the potential to benefit human health through the enhanced development of new drugs and diagnostic tools.
Written by 25 authors, it described the collaboration between government, academic researchers, and disease advocacy groups that led to the ICV trial as a model of the teamwork that can speed drugs through early development, boosting their chances of being commercialized.
«To the EC and EFPIA, it was clear that the only way to restore European competitiveness in drug development was through collaboration.»
The three Ras genes found in humans — H - Ras, K - Ras and N - Ras — were among the first to be linked to cancer development, and a new study led by VCU Massey Cancer Center researcher Paul Dent, Ph.D., has shown the recently approved breast cancer drug neratinib can block the function of Ras as well as several other oncogenes through an unexpected process.
«Our preliminary results suggest that TREML4 - regulated signaling through TLR7 may be a potential drug target to limit inflammation and the development of autoimmunity.»
«This study is the first step in a potential drug development for a new class of drugs for osteoarthritis, although there are a number of hurdles we have to go through — necessarily so — before it gets nearer patients.
As early as 1969, these collaborations led to important products - directly, as with the development of diagnostics for drugs of abuse, Abuscreen; or indirectly, through the development of technologies, which later played a key role in the first isolation and characterization of the a-interferons and to Roche's patents for Roferon.
These «nanoswimmers» cross the blood — brain barrier highly efficiently, and could lead to the development of drug delivery systems that navigate through tissues and organs to target specific sites precisely.
Results show that coping with a stressful event through behavioral disengagement — giving up on dealing with the stress — or by using alcohol or drugs each significantly mediated the relationship between stress exposure and insomnia development.
Only one out of ten drugs in development makes it successfully through clinical trials, he adds.
In his current role, he combines population research and functional genomics strategies to inform drug development from preclinical through phase 3 trials.
Through these images, the team will discover exactly how the immune system molecules bind to the Ebola virus and stop it from functioning, a critical step in drug development.
Two new tuberculosis drugs are in the final stages of development, and could also help to replace those being rendered less useful through resistance, he adds.
The expert group was convened through the Alzheimer's Association Research Roundtable — an ongoing effort that brings together experts in the field from academia, industry, and government to address ways to overcome barriers to drug development.
Robotized «high - throughput screens» like this are a growing trend in drug development as they can work through massive libraries of candidate drugs quickly and accurately in a day, as opposed to the months required by manual methods.
Pharmaceutical companies, by contrast, focus most of their efforts at the other end of the drug development pipeline, moving potential drug compounds through human clinical trials into the market.
There are many stages in the drug discovery / development process from target identification, assay design, and screening through to compound optimization, pharmacology, and testing in animal models.
Pending approval through an Investigative New Drug Application, the aerosolized form of the vaccine will be evaluated for replication, safety and immunity development in a study in adults.
Founded in 2003, the Spinal Muscular Atrophy Foundation is a nonprofit organization dedicated to accelerating progress towards a treatment and cure for Spinal Muscular Atrophy through targeted funding of clinical research and novel drug development efforts.
This is especially the case with drugs for developing - world diseases, where the financial investment, both in launching and maintaining research programs and ultimately bringing a candidate drug through clinical development and to market, is very limited.
Under the agreement, Biotecnol and Cancer Research UK's Centre for Drug Development will collaborate to take forward Tb535H through a Biotecnol - sponsored first - in - man Phase I clinical trial, using Cancer Research UK's drug development expertise in return for shareholdings in BiotecDrug Development will collaborate to take forward Tb535H through a Biotecnol - sponsored first - in - man Phase I clinical trial, using Cancer Research UK's drug development expertise in return for shareholdings inDevelopment will collaborate to take forward Tb535H through a Biotecnol - sponsored first - in - man Phase I clinical trial, using Cancer Research UK's drug development expertise in return for shareholdings in Biotecdrug development expertise in return for shareholdings indevelopment expertise in return for shareholdings in Biotecnol.
The Learning Collaborative will engage a for - profit partner to advance auranofin through late stage drug development, registration and commercialization.
About the SMA Foundation Founded in 2003, the Spinal Muscular Atrophy Foundation is a nonprofit organization dedicated to accelerating progress towards a treatment for Spinal Muscular Atrophy through targeted funding of clinical research and novel drug development efforts.
We start with a compelling scientific idea or promising drug candidate from collaborators in academia and / or industry, and then efficiently advance the therapy through pre-clinical research to enable the establishment of an independent company to progress drug candidates through clinical and regulatory development to commercialization.
The Spinal Muscular Atrophy Foundation is a nonprofit organization dedicated to accelerating progress towards a treatment and cure for spinal muscular atrophy through targeted funding of clinical research and novel drug development efforts.
Anna Huttenlocher, University of Wisconsin, USA Neutrophils in the Tumor Microenvironment Neutrophils, Wounds, and Cancer Progression Stefan Kaufmann, Max Planck Institute, Germany Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells Kathryn Moore, New York University, USA MicroRNA -33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis Lalita Ramakrishnan, University of Cambridge, UK Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment Beth Stevens, Harvard University, USA Microglia: Dynamic Mediators of Synapse Development and Plasticity Do glia drive synaptic and cognitive impairment in disease?
By working in an integrated fashion, the Research Engine enables us to rapidly move our mRNA medicines through the drug discovery phase — from initial concept to development candidate (DC) nomination.
It helps us understand the genetic basis of diversity and evolutions in organisms, leading to the insight understanding into how living things evolved through stressed environments to the pathogenesis of pathogens, including identification novel drug targets and development of novel drug candidates.
He is responsible for further developing Hookipa's groundbreaking science through the development of promising product candidates — from the initial research to manufacturing of the final drug.
«We can infuse very small amounts of multiple drugs compared to what we can do intravenously or orally, and also manipulate behavioral changes through drug infusion,» says Canan Dagdeviren, the LG Electronics Career Development Assistant Professor of Media Arts and Sciences and the lead author of the paper, which appears in the Jan. 24 issue of Science Translational Medicine.
Chemotype Evolution, Carmot's proprietary technology, enables the rapid identification of novel drugs through an evolutionary discovery paradigm and has produced a pipeline of breakthrough therapeutics currently in pre-clinical development.
About the Spinal Muscular Atrophy Foundation Founded in 2003, the Spinal Muscular Atrophy Foundation is a nonprofit organization dedicated to accelerating progress towards a treatment for Spinal Muscular Atrophy through targeted funding of clinical research and novel drug development efforts.
We believe that leveraging human intuition through creation of a scientific game for drug discovery can not only provide a new avenue to discover therapeutic drugs for protein targets, but can also contribute to the development of new sophisticated algorithms to use in computer aided drug design.
BridgeBio has committed $ 30 million and a team of senior business managers to the company, while MD Anderson, through its Institute for Applied Cancer Sciences (IACS), provides intellectual property and an oncology drug development team to advance SHP2 inhibitors toward clinical studies.
An open - source content management system then would search through upwards of a billion drug combinations to find those with the greatest potential to inhibit a given tumor, or a billion hypothetical compounds to identify candidates for new drug development.