Not exact matches
One
because he made a MAJOR, impactful, amazing
discovery that changes the game of genetics, the other
because he * already worked in industry * before he got his PhD and got 3 patents during grad school, one for a marketable
drug.
Because of this extensive validation, in the Jimeno lab and elsewhere, the Wnt pathway has been a major focus of anti-cancer
drug discovery efforts.
Positive reinforcement is a must in
drug discovery, Tillyer says,
because the process requires extraordinary persistence.
There will continue to be a demand for these people, he says,
because «at the end of the day, it's a fabulous thing to be involved in
drug discovery.
This makes our
discovery promising,
because even a small increase in the ATM activity induced by the SMRT
drug can potentially translate to positive effects for patients, slowing disease progression and hopefully improving their quality of life.»
Drug discovery in academia,
because of the financial constraints, is on a much smaller scale than industry and therefore allows «hands - on» experience of several stages in the process as well as more extensive training in a single area.
The
discovery has important implications for biotechnology,
because genetically engineered bacteria and other organisms are used to produce useful molecules such as new materials and
drugs.
This approach, in which structure and activity is not linked to a specific protein target, can cause other difficulties and slow the progress of
discovery, not least
because of the difficulty of assessing relevant toxicity against host mechanisms and the inability to use structure - guided
drug - design to drive Medicinal Chemistry progress.
Patients will benefit
because researchers will be able to move more quickly from a basic research
discovery to new
drugs in the clinic.»
This distinction is critical for decision makers in the
drug discovery sphere
because, while the market for antifrailty
drugs (even unproven ones) is large, that for genuine anti-ageing
drugs - which, as the author explains, are now foreseeable - will certainly be far larger.
«But the lead author of the study... says that he is not convinced that it is just the changing climate... «It could be partly due to this chaotic rainfall, but personally I don't think it can explain such a dramatic decline in mosquitoes, to the extent we can say that the malaria mosquitoes are almost eradicated in these communities... «What we should consider is that there may be a disease among the mosquitoes, a fungi or a virus, or they're may have been some environmental changes in the communities that have resulted in a drop in the number of mosquitoes»... The research team also found anecdotal evidence that their
discovery was not an isolated case... «Other scientists are saying they can't test their
drugs because there are no children left with malaria.»»
In R. v Poirier [2016] ONCA 582 the Ontario Court of Appeal excluded the
drugs excreted from Mr. Poirier's rectum
because of the manner of the police investigation that led to its
discovery.