Summary: A day - long symposium for the promotion of IMPC lines and emphasis of the importance of mouse phenotyping & clinical and drug discovery collaboration Attended by: IMGC delegates, clinical researchers &
drug discovery researchers Hosted / funded by: RIKEN BioResource Centre
Kingston and Cassera are both members of the Virginia Tech Center for Drug Discovery, which was established last June to increase collaboration among
drug discovery researchers in varying colleges and departments.
Working on the premise that scientific research is the foundation of any technology industry, Hancock and others at UBC are writing a business proposal for an integrative centre for drug research, with an objective of developing intellectual property in drug discovery, providing training for
drug discovery researchers, and developing new technologies.
While helping make the entire industry more productive, these new programs add yet another element to the continuing education of
drug discovery researchers.
Not exact matches
The fingered bacteria was Helicobacter pylori, and since that
discovery, many
researchers have hoped to eradicate the species with
drugs or vaccines.
In the first week of the feature and continuing throughout the month, Next Wave will explore
drug discovery opportunities in industry by highlighting the experiences of
researchers working for larger and more established companies, as well as the motivations of an individual who chose a
drug discovery start - up.
For example, she developed the company's «New Medicines» venture, which takes an open approach to
drug discovery by encouraging UCB
researchers to collaborate with independent research labs outside the company.
The
discovery has powerful implications for cancer immunotherapy
researchers say: by blocking the mechanism with a
drug, it may be possible to turn the attack - suppressing cells into tumor - attacking cells.
The
researchers took this
discovery and, in an animal model, identified a
drug that is able to re-activate those immune cells and reduce brain tumor growth, thereby increasing the lifespan of mice two to three times.
In two studies, Freiburg
researchers have made new
discoveries concerning the relationship between CML and Gab2 and
drugs that can break a particular resistance to Gab2 in CML cells.
The
discovery of the new
drug target, the
researchers noted, was made possible by something very unusual about UVA.
Tracy began as an industry
researcher and within a year had moved to the
drug -
discovery department at her pharma employer.
The
discovery of an unexpected biochemical link within tumor cells should lead to clinical trials for experimental
drug treatments that indirectly target myc and that already are being evaluated in human studies, the
researchers said.
Researchers there are convinced that these technologies will increase the chance for serendipitous
discoveries, accelerate the speed of delivering new
drugs to market and advance the industry as a whole toward personalized medicine.
The
researchers»
discovery of a control switch that acts on the UPR pathway, published March 25 in the online edition of EMBO Reports, opens new
drug development avenues for treating a wide variety of diseases by modulating the UPR pathway to prevent excessive cell death.
Researchers studying the effects of general anesthesia recently made a startling
discovery: the
drugs used to knock out patients during surgery may lead to increased pain when they wake up.
He predicts that the
discovery will help
researchers develop very specific anti-inflammatory
drugs that can subtly tweak the body's immune responses by targeting distinct ubiquitin ligases and similar enzymes involved in cellular garbage disposal.
The
researchers believe that their combination of single - molecule fluorescence spectroscopy detection and their computational models offers a novel route for
drug discovery.
«The induced pluripotent stem cells we used in this study proved to be extremely useful in disease modelling, and they could offer an excellent platform for
drug discovery and testing new therapeutic targets for Alzheimer's disease in the future,» says Early Stage
Researcher Minna Oksanen, the lead author of the study.
The convergence of several factors explains the trend: cheaper genetic sequencing technologies, the
discovery of new oncogenes (genes that can cause a normal cell to become cancerous), a new generation of computers and bioinformatics that can analyze vast amounts of data, and a multibillion - dollar effort by
researchers inside and outside the pharma industry to develop targeted
drugs and companion diagnostics for cancer.
In a striking, unexpected
discovery,
researchers at Albert Einstein College of Medicine of Yeshiva University have determined that vitamin C kills
drug - resistant tuberculosis (TB) bacteria in laboratory culture.
So similar are the two that
researchers at the University of Georgia's Regenerative Bioscience Center have developed the first U.S. pig model for stroke treatments, which will provide essential preclinical data and speed the
drug discovery process.
In a striking, unexpected
discovery,
researchers have determined that vitamin C kills
drug - resistant tuberculosis (TB) bacteria in laboratory culture.
A new study finds that two common
drugs — an antidepressant and a treatment for Parkinson's disease — can influence moral decisions, a
discovery that could help unravel specific mechanisms behind aggression and eventually help
researchers design treatments for antisocial behavior.
Lead
researcher, Associate Professor Julianne Djordjevic, said she is optimistic this
discovery will provide a new avenue for the development of safer urgently needed antifungal
drugs.
The Molecular Libraries initiative of the roadmap is specifically intended to put HTS and other
drug discovery tools into the hands of academic
researchers to help them develop new research tools and
drugs.
«People do this for
drug discovery — pharmaceutical companies and biomedical
researchers will try different kinds of molecules and see which one has the best reaction.»
Now, a new study suggests the
drug may also ease the symptoms of a genetic disease called hereditary hemorrhagic telangiectasia — a
discovery that could guide
researchers to novel therapies for HHT and other vascular diseases.
«With our brain map,
researchers could look for circuitry - specific
drug discovery,» Dong said.
By gaining an understanding of this underlying mechanism, this
discovery has the potential to vastly help
researchers learn what happens at the molecular level when this mechanism is disrupted — such as in cancer or when exposed to a particular
drug.
They have contributed to breakthroughs in regenerative medicine and
drug discovery, surpassing what
researchers once thought possible.
Its
researchers made ground - breaking
discoveries, including the findings that calorie - burning brown fat may remain active in adults and that the generic
drug salsalate is a promising treatment for people with type 2 diabetes.
Three
researchers at The University of Alabama are part of work that is leading to a new direction for
drug discovery in the quest to treat Parkinson's disease.
GigaGen partners with leading academic and biopharmaceutical
researchers to advance antibody - driven
drug discovery and development programs for cancer, immune deficiency and other serious health conditions.
A promising
discovery for advanced cancer therapy reveals that the efficiency of
drug delivery in DNA nanostructures depends on their shapes, say
researchers at Missouri University of Science and Technology and the University...
A
discovery by
researchers at Houston Methodist Research Institute could lead to better
drugs to treat asthma (Credit: Wavebreakmedia / Depositphotos)
The Seeding
Drug Discovery Initiative was established by the Wellcome Trust to help researchers move early - stage drug discoveries further along the pipeline and, ultimately, towards clinical tri
Drug Discovery Initiative was established by the Wellcome Trust to help
researchers move early - stage
drug discoveries further along the pipeline and, ultimately, towards clinical tri
drug discoveries further along the pipeline and, ultimately, towards clinical trials.
A
discovery by
researchers at Houston Methodist Research Institute could lead to better
drugs to treat asthma (Credit: < a href ="https://depositphotos.com/42918869/stock-photo-woman-using-asthma-inhaler-in.html" rel="nofollow"> Wavebreakmedia / Depositphotos )
RA is a very unpleasant disease to live with so any
discoveries we can make about it are very valuable and could help future
researchers develop new, more effective
drug therapies.»
The
researchers also worked with the Open PHACTS Foundation, the outcome of a project funded by the European Innovative Medicines Initiative that is aimed at facilitating
drug discovery.
Patients will benefit because
researchers will be able to move more quickly from a basic research
discovery to new
drugs in the clinic.»
Cloudera Enterprise accelerates life sciences research and
drug discovery by putting real - time data into the hands of the clinicians,
researchers, and providers focused on personalizing the patient experience.
Since 1997, it has been our mission to provide ubiquitin proteasome pathway (UPP)
researchers with innovative tools that facilitate and accelerate
drug discovery efforts.
Being able to isolate, manipulate and image single & multiple cells in their natural environments is vital to
researchers in many fields, notably those involved in
drug discovery, early stage diagnosis and cellular force interactions making the addition of FluidFM ® to the world of AFM imaging and force spectroscopy an ideal pairing.
In the future,
researchers hope this
discovery will serve as a platform for a
drug that could prevent brain aging.
11/6/2007 UCSD
Researchers Discover Inflammation, Not Obesity, Cause of Insulin Resistance Findings may have important potential for new
drug discoveries in fight against Type 2 diabetes
Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that inflammation provoked by immune cells called macrop... More...
In a paper published in Nature Biotechnology,
researchers from the Broad Institute of MIT and Harvard and the Dana - Farber Cancer Institute describe a new method that dramatically simplifies an arduous experimental process in early
drug discovery.
They provide
researchers with access to additional skills, medicinal chemistry, pharmacokinetics, and evaluations of
drug - like properties, which helps them determine whether their
discoveries could lead to viable
drugs to treat diseases.
To tackle BACE1,
researchers at Schering - Plough decided to use fragment - based lead
discovery (FBLD)-- a relatively new approach to
drug discovery at the time.
In a
discovery that may help scientists design new cancer
drugs, Howard Hughes Medical Institute
researchers have provided scientists with the first definitive look at how the catalytic center of the...