In general,
drug discovery starts with a particular disease.
In the first week of the feature and continuing throughout the month, Next Wave will explore drug discovery opportunities in industry by highlighting the experiences of researchers working for larger and more established companies, as well as the motivations of an individual who chose
a drug discovery start - up.
SciLifeLab and the EU Lead Factory, a collaborative public - private partnership aiming to deliver innovative
drug discovery starting points by e.g. giving free access to up to 500,000 novel compounds, declare to exploit the complementarity and synergistic -LSB-...]
Not exact matches
Like many tales of
drug discovery, the statin story
starts in a petri dish.
Creating Our Own Luck
Drug discovery today often
starts with a library of chemical compounds that includes thousands of known
drugs.
Earlier last year, the PharmBio Growth fund — which is managed by the Economic Development Board * (EDB)-- Chiron Corporation (USA), and Blue Dot Capital Pte Ltd jointly
started the nation's first
drug discovery company, S'Bio.
The genome analysis, which is published in the 9 May issue of Nature, also reveals blueprints for three assembly lines of hitherto unknown antibiotics, which, once identified, could be used as
starting compounds in
drug discovery.
«
Drug discovery is inherently risky, but the role of academics and
start - ups is to provide game - changing
discoveries that are the result of prolonged investigations in basic science, and can ultimately have a significant impact on human and animal health.»
However, we have found a system that allows the isolation of stem cells from the mammary gland and the investigation of their molecular features: with this knowledge in our hands we will be able to
start the
discovery of selective
drugs capable of killing the stem cells of a given tumor.
«We have already
started up parts of the operation, and are now looking to recruit scientists with
drug discovery and development expertise to our eight facilities», says Per Arvidsson, Platform Director for the Stockholm site of the DDD platform.
This will provide a rich source of chemical
starting points for CBCS scientists to translate novel biology into innovative
drug discovery project, which may one day result in new medicines for patients in need,» said Garry Pairaudeau, Head of External Sciences, Innovative Medicines and Early Development Biotech Unit at AstraZeneca.
In creating Vescor, Deerfield and MD Anderson aim to perform
drug discovery and development in a markedly different way than traditional oncology
start - ups.
An emerging strategy in early
drug discovery entails using fragments, i.e. molecules smaller than conventional
drug candidates, as
starting points for design of novel therapeutic compounds.
«We
started with a big question: how do scientific
discoveries lay the foundation for successful development of new
drugs?»
Our goal is to kick -
start the
drug discovery process as early as possible by removing translational delays in the transition of
drug development from bench to bedside.
«I think we're at the
start of an exciting journey of
drug discovery for a new class of antithrombotic therapies.»
Mike Friedlander, the executive director of the Virginia Tech Carilion Research Institute (VTCRI) and associate provost for health sciences, and David Kingston, a University Distinguished Professor and director of the new Virginia Tech Center for
Drug Discovery (VTCDD), presented an overview to the Board of Visitors about Virginia Tech advances in human health, novel research programs, technology licensing, start - up companies, and drug discovery and developm
Drug Discovery (VTCDD), presented an overview to the Board of Visitors about Virginia Tech advances in human health, novel research programs, technology licensing,
start - up companies, and
drug discovery and developm
drug discovery and development.
Another reason why EPA
started with estrogen was that high - throughput in vitro assays were already developed either commercially for use in
drug discovery by the pharmaceutical industry or through an interagency government effort called Toxicology Testing in the 21st Century, or Tox21.
«I think we're at the
start of an exciting journey of
drug discovery for a new class of antithrombotic therapies,» said lead study author Stephen Holly, PhD, assistant professor of biochemistry and biophysics at the University of North Carolina School of Medicine.
Doubly the outsider in the WASP Ivy League, Ginsberg stumbles toward self -
discovery in the company of the campus eccentrics,
starting with Carr, who declaims Henry Miller from a table in the college library; he introduces Ginsberg to Burroughs, scion of wealth with access to a pharmacy of mood - altering
drugs; and finally to Jack Kerouac (Jack Huston), the all - American boy with a mad passion to burn like a Roman candle.