TUESDAY, April 17, 2018 (HealthDay News)-- In a small, early study, a nasal spray containing the club
drug ketamine appears to quickly help ease depression and even curb thoughts of suicide.
In the past month alone, studies have been published on the benefits of MDMA (better known as Ecstasy) in people with post-traumatic stress disorder and on the fast - acting antidepressive effects of the club
drug ketamine (aka «Special K»).
The researchers found that by blocking NMDA receptors with
the drug ketamine, they could elicit rapid antidepressant effects in patients with treatment - resistant depression.
Mouse experiments with the popular club
drug ketamine may be skewed by the sex of the researcher performing them, a study suggests.
Not exact matches
By the way, let's just understand each other: [Johnson & Johnson], which reports [Tuesday], has a new
ketamine drug that is past Phase 2 and I think that is going to be remarkable.
Ketamine users could face significantly higher jail sentences, after government advisers suggested the
drug be upgraded to Class B from Class C.
Because people take a lot of it - and often take it with other
drugs such as
ketamine - it can also cause blood vessels to narrow and bring on a cardiac arrest.»
During that window of opportunity, other
drugs and therapies would be introduced to ward off relapse, perhaps aided by an occasional
ketamine booster.
He knew that
ketamine, used as an anesthetic during the Vietnam War, frequently produced out - of - body experiences and that other
drugs were suspected of being triggers as well.
When eight male and eight female researchers injected mice with
ketamine, they saw the same results: mice injected by women did not respond to the
drug.
These were thought to be
ketamine's target, but clinical trials of other
drugs that target them have largely yielded disappointing effects on depression, says Gould.
Ketamine was developed as an anesthetic, but is better known publicly for its abuse as the party drug Special K. Researchers are now seeking alternatives because ketamine can produce side effects that include hallucinations and the potential for abuse — limiting its utility as an antidep
Ketamine was developed as an anesthetic, but is better known publicly for its abuse as the party
drug Special K. Researchers are now seeking alternatives because
ketamine can produce side effects that include hallucinations and the potential for abuse — limiting its utility as an antidep
ketamine can produce side effects that include hallucinations and the potential for abuse — limiting its utility as an antidepressant.
If the same result holds true in humans, it could provide an explanation for why
drugs that target NMDA receptors have failed to capture
ketamine's full effects.
Ketamine has also been a
drug of abuse and can lead to untoward psychiatric or cognitive problems when misused.
Gould and his colleagues used a battery of behavioural tests in mice to show that one of
ketamine's breakdown products — a compound called (2R, 6 R)- hydroxynorketamine — is responsible for much of the
drug's antidepressant effects.
In addition, research now shows that a number of medicinal and recreational
drugs can mirror the euphoria often felt in near - death experiences, such as the anesthetic
ketamine, which can also trigger out - of - body experiences and hallucinations.
Ketamine affects the brain's opioid system, which can naturally become active even without
drugs when animals are under attack, suggesting trauma might set off this aspect of near - death experiences, Mobbs explains.
Using the forced swim test, they found that mice given 10 milligrams per kilogram of injected
ketamine floated for about 75 seconds compared with 110 seconds for mice not given the
drug.
Mice without Narp not given the
drug floated for about 110 seconds, whereas Narp-less mice given
ketamine floated for about 90 seconds.
While the effects of some substances that have become popular as recreational
drugs in recent years have previously been studied for their potential medical use, such as
ketamine and GHB, there are practically no published studies on mephedrone — just user surveys and anecdotal accounts.
«Enhancing AMPA receptor function has been a target for antidepressant
drug development for some time; what is novel is that
ketamine may act in this way.
Ketamine, a medication originally developed as an anesthetic
drug, is now being used to address treatment - resistant depression.
This account of a man whose depression spiraled out of control positions
ketamine as the one
drug that saved him, his marriage, and his relationships.
The biggest development has been the rediscovery of a promising, yet fraught,
drug called
ketamine.
Montana Psychiatry and Brain Health Center has
Ketamine treatment for
drug - resistant depression, Neuragain, Billings, Montana, Dr. Erin Amato.
The Orlando Humane Society restricted access to its
drug supply Wednesday under scrutiny following the theft of 30 vials of the animal tranquilizer known as
Ketamine or «Special K. «State inspectors and Orange County sheriff's investigators studied the society's
drug inventories, purchase orders and logs to assess the recent break - ins at the agency's two clinics.Under new guidelines, access to ordering, receiving, using and stocking controlled substances will be restricted by requiring two authorized signatures on all incoming supplies.
Common Feline Anesthetic May Cause Brain Damage: Several studies have hinted that use of
ketamine, an anesthetic
drug closely related to PCP («angel dust») in children may result in alterations in learning ability and memory.
We use an injectable
drug combination of telazol,
ketamine and xylazine, which means that anesthetic duration is limited.
But
Ketamine is not just being used on animals but it is also used on the street as a date rape
drug.
Common pharmaceuticals range from opioids and nonsteroidal anti-inflammatory
drugs (NSAIDs) to α2 - agonists, gabapentin, amantadine,
ketamine, and local anesthetics.
Montana Psychiatry and Brain Health Center has
Ketamine treatment for
drug - resistant depression, Neuragain, Billings, Montana, Dr. Erin Amato.
The eleven cibachrome prints in The
Drug Series — Crack, Cocaine, Heroin, Marijuana, LSD, Psilocybin,
Ketamine, Ecstasy, Amphetamine, Hashish, and Mescaline — depict a cross-cultural sample of adults ranging in age from 24 to28 years who had little or no prior experience with
drugs.
Criminal offences arising from possession, trafficking and production of
drugs such as marihuana, cocaine, heroin,
ketamine, methamphetamine, oxycodone and oxycontin are handed by the federal prosecution service, and are prosecuted very aggressively.
Montana Psychiatry and Brain Health Center has
Ketamine treatment for
drug - resistant depression, Neuragain, Billings, Montana, Dr. Erin Amato.
Montana Psychiatry and Brain Health Center has
Ketamine treatment for
drug - resistant depression, Neuragain, Billings, Montana, Dr. Erin Amato.