Sentences with phrase «drug outcomes resulting»

It also alludes to the complex phenotypes and rare drug outcomes resulting from rare pharmacogenomic variants.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

The Grocery Manufacturers Association (GMA) last week urged the Food and Drug Administration to ensure any proposed long - term sodium reduction targets are based on a review of the Dietary Reference Intake (DRI) for sodium, future knowledge gained from work on the short - term sodium reduction targets, results of new research that will become available on human health outcomes and dietary sodium intake, and the emergence of new technologies that allows sodium reduction targets to be safely and effectively achieved.

After the positive results from a random drug test, she was pulled from her security post at Gracie Mansion and remains on paid desk duty in Queens pending the outcome of the trial.

He further stated that the outcome of the result would assist him to move a motion in the Senate that public officers and their appointees should be undergoing psychiatric and drug related tests from time to time.

«We had thought that previous trials may have been limited by their use of first - generation drug - eluting stents, but these results show CABG still leads to better outcomes.»

«When we heard that patient outcomes are held back by fear of hypoglycemia (low blood sugar), we created drugs that result in a reduced risk of hypoglycemia,» he says.

As a result of a 2007 law, within 1 year of the completion of a trial, drug companies must also submit summary results that include information such as the number of participants, their age and gender, outcomes, and adverse events.

The drug — named mepolizumab — can replace traditional, steroid - based treatments for a specific subset of patients, resulting in improved outcomes and reduced side effects.

When outcomes from these two groups were added together, the absence of any benefit from drug therapy in patients with an unwitnessed arrest may have muted the significant benefit seen in those with a witnessed cardiac arrest, resulting in the marginal overall outcome of the study.»

In addition, patients with bovine TB often do not respond to the drugs commonly used to treat TB, sometimes resulting in a fatal outcome.

«The lack of association between response rates and hard clinical outcomes raises concerns about fast track approval of new drugs, based on results from trials utilizing solely these surrogate markers,» the researchers wrote.

This can occur due to a lack of consideration of the disease process, inadequate use of diagnostic testing, client pressures or the perceived need to «do something» — the perception that if veterinarians don't use antibiotics and a bad outcome results, it's the practitioner's fault, but the drug is at fault if a complication from antibiotics develops, Weese added.

The results of this study also make it clear that the negative effects of break - up can extend beyond simply feeling sad or lonely, and can coincide with much more potentially serious outcomes, especially when you consider the serious consequences associated with criminal behavior, drinking, and drug use.

This could be an artifact caused by premature mortality in people with multiple adverse childhood exposures; the clustering of multiple risk factors among people with multiple childhood exposures is consistent with this hypothesis.29 Thus, this potential weakness may have resulted in underestimates of the true relationships between ACEs and the illicit drug use outcomes.41

It found that diversion treatment programs for offenders with drug and alcohol problems save money and result in better health outcomes and lower recidivism rates.

Results demonstrated significantly better outcomes than those who received treatment - as - usual on trauma related symptoms, although not on alcohol or drug use.

Adolescent FBT's goal is to result in positive outcomes in such areas as alcohol and drug use, depression, conduct problems, family dysfunction, and days absent from work / school.