Sentences with phrase «drug rifampicin»

The study followed 1,055 household contacts of 213 individuals with MDRTB infection (defined by resistance to the drugs rifampicin and isoniazid), and 2,362 household contacts of 487 individuals with drug - susceptible tuberculosis for up to three years.

Not exact matches

Vitamin C had no activity by itself, but in two independent experiments, the combination of vitamin C with the first - line TB drugs, isoniazid and rifampicin, reduced the organ burdens faster than the two drugs without vitamin C, said first author Catherine J. Vilcheze, Ph.D..

But two forms of tuberculosis, referred to as «multi-drug-resistant,» or MDR, and «extensively drug - resistant,» or XDR, have become resistant to rifampicin.

Rifampicin and related drugs are important antibiotics, the key to an effective «drug cocktail» that already takes about six months of treatment to cure tuberculosis, even if everything goes well.

Drug resistance in rifampicin and related antibiotics has occurred when their bacterial RNA polymerase enzymes mutate, Mahmud said, leaving them largely unaffected by antibiotics that work by inhibiting RNA synthesis.

«Our study clearly showed that not a single pharmacy gave away first line anti-TB drugs (isoniazid, rifampicin, ethambutol, pyrazinamide and streptomycin) without prescriptions.

The anti-angiogenesis drugs also increased the effectiveness of rifampicin, a first - line TB therapy.

The intensive treatment for pulmonary TB is a six - month regime that consists of two months of isoniazid, rifampicin, pyrazinamide, and ethambutol, followed by four months of isoniazid and rifampicin in FDCs that are combined in one tablet, or separately as single - drug formulations.

Her research on immune reconstitution inflammatory syndrome and rifampicin - efavirenz drug interactions has been influential in defining treatment strategies for these common complications of integrating TB - HIV treatment.