In the most convincing study to date, a team of researchers in Cambridge has shown that a diet high in soya protein can alter women's hormones in a way that mimics the effects of the
anticancer drug tamoxifen.
Two types of
anti-estrogen drugs Tamoxifen (Nolvadex) and raloxifene (Evista) are part of a drug class called selective estrogen receptor modulators (SERMs).
Indeed, another experiment in live mice showed that the estrogen -
blocking drug tamoxifen slashed platelet counts by 45 % within 9 days.
Turmeric is so powerful, that studies have suggested the effects of this herb may be equally or more effective than the pharmaceutical estrogen -
lowering drug tamoxifen.
Another study published in the journal Cancer Biotherapy and Biopharmaceuticals found that FWGE in conjunction with the ER + breast cancer
chemotherapy drug Tamoxifen «significantly increased apoptosis already 24 hours after starting treatment.»
Sky News star JACQUIE BELTRAO reveals how the breast cancer
drug Tamoxifen which saved her life also Dream: Dream, a hallucinatory experience that occurs during sleep.
More effective treatments for breast cancer may follow now that researchers have discovered a second mode of action for the
anticancer drug tamoxifen.
For example, the
anti-estrogen drug tamoxifen, prescribed for breast cancer treatment, has been used by men to oppose the estrogenic effects of anabolic steroids.
Using
the drug tamoxifen — an estrogen receptor modulator used to treat breast cancer — the scientists were then able to prompt an enzyme suspended by an estrogen receptor in the cytoplasm of the mouse's neuronal cells to migrate into the nucleus and restore the gene's function.
Researchers led by Xiao - Jiang Li, MD, PhD and Shihua Li, MD, at Emory University School of Medicine, used genetically engineered mice in which the huntingtin gene can be deleted, triggered only when the mice are given
the drug tamoxifen.
Curiously,
the drug tamoxifen, which usually blocks estrogen effects, also darkened skin.
Of these variants, reported today in the journals Nature and Nature Genetics, 65 are common variants that predispose to breast cancer and a further seven predispose specifically to oestrogen - receptor negative breast cancer - the subset of cases that do not respond to hormonal therapies, such as
the drug tamoxifen.
All the mice were given
the drug tamoxifen.
Hill co-authored one of the most startling studies in the field in July 2014, when he reported in the journal Cancer Research that
the drug tamoxifen is rendered completely ineffective against human breast cancer in mice when they are exposed to dim light at night.
The gene was then turned on with an injection of
the drug tamoxifen.
Healthy women in the US and Canada are soon to begin a trial of
the drug tamoxifen to see whether it prevents breast cancer.
Key research that could provide a better picture of the risks of taking
the drug tamoxifen will take only a year to complete, yet a large trial of the drug in healthy women will probably go ahead in a few weeks.
But recent work shows that while these cancers lack estrogen receptors, progesterone receptors, and aren't driven by the gene HER2, up to a third of these tumors express the androgen receptor — clinical trials are underway to inhibit the androgen receptor in these tumors in much the same way that
the drug Tamoxifen inhibits estrogen receptor in estrogen - receptor - positive breast cancers.
The researchers say that breast - feeding could be the equivalent of taking
the drug tamoxifen for 5 years, which is a well - known way to cut breast cancer risk in women with a family history of the disease.
Dietary estrogens in the form of soy foods were found to have the potential to disrupt the endocrine system with the effects in women similar to taking the breast cancer
drug tamoxifen (Proceedings of the Society for Experimental Biology and Medicine 1995 Jan; 208 (1): 51 - 9).
In a surprising recent study, methylparaben was found to block the breast cancer
drug tamoxifen (more).
The activity of the TBG could be increased in women on birth control pills, hormone replacement therapy, during pregnancy, those with liver diseases, genetic predisposition and those who take
the drugs tamoxifen or perphenazine.
A comparison was made between the effects of lowering sugar consumption and the effects of
the drug tamoxifen.