Sentences with phrase «drugs at lower doses»

It is a technique used by physicians that fight kidney rejection and autoimmune diseases of many sort — give multiple drugs at lower doses rather than single drugs at high doses.

Not exact matches

Separately, a Food and Drug Administration panel recommended that an experimental rheumatoid arthritis drug developed by Lilly and Incyte should only be approved at a lower dDrug Administration panel recommended that an experimental rheumatoid arthritis drug developed by Lilly and Incyte should only be approved at a lower ddrug developed by Lilly and Incyte should only be approved at a lower dose.

BERLIN German dialysis specialist Fresenius Medical Care cut its 2018 sales target due to lower than expected doses of calcimimetic drugs at its dialysis service business in the United States.

The drug also reduced their testosterone levels at both low and high doses.

Widespread concern and public pressure — combined with growing science on arsenic's toxicity at low doses — should have spurred the U.S. Food and Drug Administration (FDA) and the cereal industry to take high - arsenic cereals off store shelves.

«The median percentage reduction in seizure frequency was more than 29 percent for patients on a low - dose regimen of everolimus and nearly 40 percent for patients with high - dose regimen to the drug,» says David Franz, MD, founding director of the TSC Clinic at Cincinnati Children's Hospital Medical Center and the study's senior author.

These antianxiety drugs «are known to be safe, and we are using them at very low levels here,» study author Scheuer notes, adding he is not concerned about human patients receiving low doses of antianxiety drugs off - label.

«Our preclinical data suggest that combining low doses of these inhibitors will enhance the clinical effects of both drugs as a potential treatment for patients with AML,» says the senior author, Feyruz V. Rassool, PhD, associate professor of radiation oncology at the University of Maryland School of Medicine (UM SOM) and a researcher at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC).

It can be used to wean addicts off their drug of choice, and then is either discontinued or continued at a lower, maintenance dose.

People are increasingly taking daily, low doses of illegal psychedelic drugs to up their game at work and improve their mood.

The response we've seen in flies to low doses of lithium is very encouraging and our next step is to look at targeting GSK - 3 in more complex animals with the aim of eventually developing a drug regime to test in humans.

New research conducted at the Center for Tuberculosis Research at the Johns Hopkins University School of Medicine shows that lower doses of the toxic drug bedaquiline — given together with verapamil, a medication that's used to treat various heart conditions — can lead to the same antibacterial effects as higher toxic doses of bedaquiline.

Scientists at the U.S. Food and Drug Administration have found that bisphenol A does not affect the health of rats fed low doses.

The approach, called a «metronomic dosage regimen,» uses significantly lower doses of chemotherapeutic drugs but at more frequent time intervals.

The low doses, careful targeting of the drugs and their ability to work in synergy at the same time appeared to greatly increase their effectiveness, while almost completely eliminating toxicity.

At low doses, the drug just makes people feel relaxed.

This therapeutic effect was enhanced by combining the Angiopoietin - 2 antibody with a so - called metronomic chemotherapy: In this kind of therapy, chemotherapeutic drugs are given continuously at much lower dose as in the classical high - dose chemotherapy.

«We tested combinations because lower doses of each drug can be used, potentially decreasing side effects,» said Dr. Fish, a Professor in the Department of Immunology at the University of Toronto.

Another concern is that people might have allergies to drugs like antibiotics, and endocrine disruptors like PFASs and flame retardants may produce effects at much lower doses than previously thought.

Methotrexate is already used as a chemotherapy drug for several types of cancer, and this early research shows that at much lower doses it could have the potential to help treat certain blood disorders.»

When used in solid organ transplants at UPMC, this protocol allows patients to be treated with low doses of a single maintenance drug.

Methylnaltrexone, a drug designed to reverse one of the most troubling problems caused by opium - based analgesics without interfering with pain relief, is rapidly effective at low doses with no apparent side effects report researchers from the University of Chicago Medical Center in the January 19, 2000, issue of JAMA.

January 18, 2000 Drug blocks opioid side effects: Could improve palliative care Methylnaltrexone can reverse opioid - induced constipation without interfering with pain relief, is rapidly effective at low doses and has no apparent side effects.

Instead, «health care providers should regularly review their older patients» drug regimens — including over-the-counter medications — to look for chances to use fewer anticholinergic medications at lower doses,» she advised.

At some drug stores, the price for a three - month supply of the lowest starting dose (5 mg) of bisoprolol fumarate is about $ 140, while another beta - blocker, atenolol, costs only around $ 20 for the lowest starting dose (25 mg)..

The drug is much more effective, even at lower doses, if you follow a healthy lifestyle,» he adds.

Dose selection for an elderly patient start at the low end of the dosing range (1 - 2 suppository (s) per day) reflecting a consideration of concomitant disease or other drug therapy.

This means that at low doses of statin drugs CoQ10 depletion may not be a significant concern.

They opted for higher doses of pramlintide (240 ug TID [three times per day]-RRB- because in dose - escalation studies, the incidence and severity of adverse drug reactions was consistently low at all doses tested.

While these drugs are generally considered safe and effective at the low doses used for heartworm prevention, there are always exceptions.

To avoid these problems, it is best to test the drug in your pet at low levels for a week or two before graduating to a full therapeutic dose.

A potent anti-inflammatory drug, Medrol relieves itching quickly and can typically be given at lower doses than other corticosteroids.

Given the low cost and open availability of such drugs, many owners would prefer to dose their dogs at home rather than put their dogs through a stressful and expensive visit to the veterinarian.

The two drugs in combination haven proven to be highly effective, and since each of these drugs is at a low dose side effects are rare.

Children should be monitored carefully for metabolic effects predisposing them to diabetes, and use of the drug should be at the lowest possible dose for the shortest possible time,» said one of the study's senior authors, Wayne A. Ray, Ph.D..