Sentences with phrase «drugs dabrafenib»
Not exact matches
In a randomized, phase 2 multi-center clinical study, led by Manisha Shah, MD of The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone compared with the same drug given in combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf mutations.
https://www.sciencedaily.com/
Around 40 to 50 per cent of melanoma patients have a faulty BRAF gene and they can be treated with the targeted drugs vemurafenib or dabrafenib.
These are the BRAF - targeted oral drugs, dabrafenib and trametinib.
«These new data, demonstrating the impact of nivolumab and of dabrafenib and trametinib on stopping melanoma coming back, show how we might use these drugs earlier in the course of the disease.
«What we find is that dabrafenib, even at high doses, does not fully turn off the MAPK pathway, thereby enabling eventual escape from drug,» Spencer says.