When BPTF is knocked out in mouse mammary stem cells early in pregnancy, however, there is a drastic decline in the number
ductal structures (right side).
Secretion of the hormones estrogen and progesterone set the stage for dramatic changes that take place in the breast during pregnancy: a massive proliferation of mammary epithelial cells, and the formation of thousands of
ductal structures, which support milk production and transport during lactation.
This interaction causes the myoepithelial cells — on the outer layer of
the ductal structure — to contract, squeezing the luminal cells within.
Not exact matches
«The invasive
structures we observed in our stiff matrices resemble the morphology of early - stage invasive
ductal carcinoma.