Sentences with phrase «duration of time more»

The beach has been closed to the public for a long duration of time more than once.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

The duration of a rate lock depends on the agreement you arrive at with your lender; usually it lasts for 30 or 60 days, but a lock can be issued for longer periods of time if the underlying deal being funded is more complex and requires more time to close.

But for the more liquidity - focused part of an asset allocation strategy, now may be a good time for short - duration products.

It is really about picking up nearly 2 percentage points more of yield while waiting for Mr. Carney to act on rates, at which time, it would be best to switch to shorter duration holdings.

But for the more liquidity - focused part of an asset allocation strategy, now may be a good time to consider investment - grade short - duration products.

Because the repayment term is longer, interest has more time to add up and you can end up paying thousands more over the duration of your loan.

If you are a prodigious saver, are willing to keep your money safe for a set duration of time while earning an interest rate above the current risk free rate 10 Year Treasury, and are concurrently investing in other more aggressive instruments, I recommend diversifying your capital into a 5 - year CD account or longer duration.

Date: Thursday, April 26, 2018 Time: 8:00 pm EDT Duration: Maximum of 30 minutes (The actual impact should be less than... [Read more]

In terms of Time its whole planetary duration is no more than a flash in the huge course of sidereal development.

Time, or more accurately, becoming seems to be more fundamental in the light of available evidence, while spatial relations are mere instantaneous cross-sections in what Whitehead called the «creative advance of nature» and Bergson, before him, «true duration.»

The signing was viewed as a letdown in Dortmund at the time when he signed as Lewandowski's replacement, & then for the duration of his first season - after which 2 more strikers were brought in - including Ciro Immobile.

And ironically, parents» sleep efficiency is not related to the number of times they're woken, but to their overall stress; e.g., mothers who exclusively breastfeed wake more often but have better quality and duration of sleep.

Research shows that when a mother has the support and encouragement of her partner, she's more likely to be successful at breastfeeding and breastfeed for a longer duration of time.

And it's better for you and your baby because when you feel more comfortable breastfeeding in a variety of different situations, you're more likely to breastfeed exclusively and for a longer duration of time.

Babies arouse more frequently, but for shorter average durations than if the baby slept apart - and spend less time in deeper stages of sleep which may not be beneficial for babies with arousal deficiencies - as also shown in recently published refereed articles.

A more recent study found that full - time work decreased both initiation and duration of breastfeeding, while part - time work had no effect on either (Fein and Roe, 1998).

Of the 33 % who used the shield for the duration of breastfeeding, 11 % said the baby would have breastfed without it at any time but continued using it because breastfeeding felt more comfortable with iOf the 33 % who used the shield for the duration of breastfeeding, 11 % said the baby would have breastfed without it at any time but continued using it because breastfeeding felt more comfortable with iof breastfeeding, 11 % said the baby would have breastfed without it at any time but continued using it because breastfeeding felt more comfortable with it.

For mothers who enjoy sharing sweet dreams with your baby, the research is affirming — touch and proximity are essential elements of bonding; the hormonal status that enhances bonding is at its most effective during night - time breastfeeding; continued breastfeeding maintains the release of hormones essential for mother - infant bonding, and breastfeeding is more likely to be successful for a longer duration when mothers and infants share sleep.

Additional reasons for deciding not to breastfeed can include concern about the quality and quantity of breast milk, and partner and family support, which are common across developed and developing countries.10, 11 Women who decide not to breastfeed are also more likely to have smoked during their pregnancy, be primiparous mothers (i.e., having their first child), and to have a child born low birth weight or with complex health issues such as cystic fibrosis.9, 12 Prenatal and post-natal stressful experiences may also reduce the duration of breastfeeding.13 Finally, several studies suggest that mother's who return to work within the first 6 months postpartum or anticipate an early return to full - time employment, are less likely to breastfeed.

«Other changes I think over the duration of my time being here seeing a switch to a lot more dark chocolate as compared to milk chocolate.

«Advances in numerical algorithms, automatic grid generation, and increased supercomputer power will eventually make the simulations of flood waves over large durations of time possible using Titan, and even more so with Summit,» Constantinescu said.

Results show that later sleep times were associated with more self - reported minutes sitting, and sleep timing remained a significant predictor of sedentary minutes after controlling for age and sleep duration.

Aspirin use was associated with a 47 % reduced risk of cervical cancer among frequent users — those who used aspirin seven or more times a week, regardless of duration — and 41 % reduced risk among long - term frequent users — those with five or more years of frequent use.

The odds of reaching recommended levels of leisure - time physical activity increased from 60 to 900 percent, depending on whether adult residents were former or current members of the program, and if the duration of their participation lasted for less than six months or for six or more months.

The team has operated Opportunity on Mars for more than 50 times longer than the originally planned mission duration of three months.

«Next, we need to understand more precisely what the optimal timing, dose and duration of NSAID use should be among patients with KRAS wild - type tumors.

The delay in school start time was associated with a significant (29 minute) increase in sleep duration on school nights, with the percentage of students receiving eight or more hours of sleep on a school night jumping from 18 to 44 percent.

Evidence for regional warmth during medieval times can be found in a diverse but more limited set of records including ice cores, tree rings, marine sediments, and historical sources from Europe and Asia, but the exact timing and duration of warm periods may have varied from region to region, and the magnitude and geographic extent of the warmth are uncertain.

The estimation method may be a more complex time judgment, because it implies the quantification of duration in time units while the comparison method only requires a comparison between durations [8].

We have to understand that in order to gain muscles, we have to make sure that, yes, our protein intake is quite high but, more importantly, that we are lifting heavy weights in the gym following a consistent, efficient hypertrophy program that takes into consideration the number of sets and repetitions, the tempo, the training volume, the time under tension, the duration of rest between the sets, etc., etc..

This yoga ought to be achieved for at least ten times for more than a duration of a single month.

Creatine also increases the amount of time that maximal output can be performed — for example, it may increase the duration of a heavy lift, which means more repetitions at the same weight.

If you have been exercising consistently prior to starting Medifast, it is recommended that you reduce your intensity and duration of exercise for the first couple of weeks so your body can adjust to your lower calorie levels, and do no more than 45 minutes of vigorous exercise each day during this time period.

A recent 2015 study of older men also found that lower vitamin D levels were associated with shorter sleep duration and more time spent awake after initially falling asleep.

By using a lighter weight, higher repetitions, and varying the repetition duration, you can maintain the stimulus for a prolonged period of time and theoretically, you should be able to expend more energy than just pumping out a lower number of reps with high volume training.

New Recommendations from the National Sleep Foundation - The Atlantic January 2015 - Poor Sleep in Adolescence Predicts Future Problems, Study Says - Los Angeles Times January 2015 - How Sleep Keeps You Healthy, Helps You Heal - Discovery News September 2014 - Lack of Sleep Increases Risk of Failure in School Among Teens - Science World Report, from Sleep Medicine August 2014 - Sleep Woes in Old Age May Be Linked to Brain Cell Loss - Health magazine August 2014 — University of Chicago Study: Getting More Sleep Could Cut Junk Food Cravings in Half — CBS News August 2014 — University of Montreal Study Shows Learning Is Best Enhanced During Sleep - Jewish Business News February 2014 - Link Found between Sleep Duration and Depression - Psych Central February 2014 - Less Sleep, More Time Online, Raises Risk for Teen Depression — National Public Radio

If that's the case then I practice it too, such as eating at least 4 - 5 hours before bedtime so that the duration of time without food is more than 12 hours (assuming 8 hours of sleep) plus I have a very light «dinner», a small salad plus vegetables juicing only.

Creatine also increases the amount of time that maximal output can be performed - for example, it may increase the duration of a heavy lift, which means more repetitions at the same weight.

And to add insult to injury, sleep quality and duration decline as we grow older - at a time when we need the health benefits of a good night's rest more than ever.

This agreement must contain all the details ranging from physical relation, financial relation, meeting timings, duration of the relationship and many more.

It is, as such, not surprising to note that A Most Wanted Man remains hopelessly, utterly uninvolving for the duration of its often interminable running time, with the who - cares - about - any - of - this vibe ensuring that the film only grows more and more exasperating as time slowly progresses.

Cast Size 24 but easily adjustable up or down (information can be split up between several more children taking cast size to 30) Duration Around 10 minutes reading time — this does not include music suggestions and «song performances» Following is a review from publisher contact: A short play giving a lot of information about the land down under: some history, some wildlife, some music and some facts and figures to round it all out.

Modified ESL Program The ESL director modified the ESL program so that it was more purposeful and of time - limited duration.

Compared with the last - gen TT RS, the 2.5 - liter turbo five in the new - for - 2018 model breathes better (thanks to new cylinder head with variable valve lift and duration timing on the exhaust cam), weighs nearly 60 pounds less (an aluminum block, magnesium upper sump, and other fat - reducing measures), and makes considerably more power, the byproduct of new port fuel injection and an increase in boost pressure from 18.1 to 19.6 psi.

Add to that the details we were being provided by the engineer about the high - tech, fragile - sounding stuff inside the engine — the «i - VTEC,» a system of «intelligent» valve timing that allows all 16 valves to open and close at precisely the correct time, for precisely the correct duration; a compression ratio of 11:1, more like a race - car engine than a passenger car; and a fuel injection system so sophisticated that rocket scientists would be scratching their heads.

Costing more than $ 100,000 each, the crash dummies are wired with sensors that transmit dozens of continuous measurements to a computer that records a stream of data 4,000 times during the two - fifths - of - a-second duration of a crash.

If publishers resorted to the subscription model, I would jump on it like the avid reader I am... I read more than three or four books a week and usually more than one book at a time; usually one fiction and a couple of nonfiction depending on the duration of time I have to read.

iPads will be of more help to those who are required to stay at the hospital for longer duration of time.

When it comes to rental durations, you have the option of choosing semester, quarter or short term, making it more convenient for those who would like some kind of flexibility on the amount of time they'd like to rent their textbook for.