Sentences with phrase «duration rates decrease»

While breastfeeding initiation rates are high in the region and program, duration rates decrease sharply at six months.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

For example, a 3 - year duration means a bond will decrease in value by 3 % if interest rates rise one percent, or increase in value by 3 % if interest rates fall one percent.

A review of current randomized controlled trials suggest that the benefits of holding for preterm babies include shortened hospital stay, decreased illness, higher exclusive breastfeeding rates / longer breastfeeding duration, increased weight gain, improved temperature regulation, and improved maternal sense of competence.

Although not directly comparable, our findings are in broad agreement with those from routine data in Scotland that have indicated a positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our findings reinforce those of Coutinho and colleagues who reported that high exclusive breastfeeding rates achieved in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based intervention.

This argument also seems to allow formula companies and health professionals to pass out formula company literature and free samples of formula to pregnant women and new mothers without pangs of guilt, despite the fact that it has been well demonstrated that this literature and the free samples decrease the rate and duration of breastfeeding.

Fertility tests of the mice in adulthood showed that those whose mothers had been fed a high - fat diet while breastfeeding had decreased litter size, longer duration from mating to date of birth and impaired pregnancy rate in both female and male mice.

Fertility tests of the mice in adulthood showed that those whose mothers had been fed a high - fat diet while breastfeeding had decreased litter size, longer duration from mating to date of birth and impaired pregnancy rate in both female and male mice.

Mills» group previously found that winter white snowshoe hares confronting snowless ground have higher mortality rates that could drive massive population declines as snow duration continues to decrease.

More specifically, peak firing rates in the recruited population decrease systematically with increasing saccade amplitude while burst duration and skewness increase with increasing saccade amplitude.

Soccer's global governing body, FIFA, has found that a dynamic, movement - focused warmup of similar duration (they call their 20 - minute warmup for youth players «11 +») decreases overall injury rate by 48 percent and serious injuries by 74 percent.

For example, if short - term rates were to rise 1 %, you would lose about 2 % on a short - term bond fund (assuming a 2 year duration), and your total return over 1 year would be about 0 % (2 % interest minus 2 % decrease in value).

In this case, a 1 % rise in interest rates would cause about a 9 % (1 % times duration of 9), decrease in the principal value of the note from 100 to 91.

For example, a two - year duration means that the bond will decrease in value by 2 % if interest rates rise by 1 % and increase in value by 2 % if interest rates fall by 1 %.

If one believes that interest rates will decrease, taking on more duration risk can make sense.

As an example, a 5 - year duration means that a bond will decrease in value by 5 % if interest rates rise 1 % and increase in value by 5 % if interest rates fall 1 %.

And the big caveat here is that longer duration bonds or bond funds (such as 20 or 30 years) are problematic regardless, because their prices will decrease much more precipitously when interest rates eventually rise.

Bond portfolio managers increase average duration when they expect rates to decline, to get the most benefit, and decrease average duration when they expect rates to rise, to minimize the negative impact.

- Adjusted abilities of some fighters and ARMS as below: Misango - Duration of immobility when masking up reduced (The Misanga is pleased) Scorpio - Increased curving, Increased expansion rate of charge attacks, Shortened wait time prior to scorpion jumping, Decreased extension speed, Decreased flotation during jump attacks, Decreased speed of charge attacks, Decreased homing during jumping attacks.

The difference is that instead of offering a locked - in amount of coverage that lasts over the entire term — the duration of the policy — the coverage decreases in value at a set rate.