Sentences with phrase «during an action potential»

we wrote that negatively charged potassium rushes out of a neuron during an action potential.

During an action potential, calcium influx into the presynaptic terminal triggers the fusion of synaptic vesicles with the plasma membrane, leading to the release of transmitter through the process of exocytosis.

Not exact matches

Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.

Of course it would be silly to suggest that winning any game, cup or otherwise, isn't good for the club, but let's remember just how problematic FA Cup success has been for this club... I'm certainly not going to suggest I didn't enjoy seeing Arsenal win, I'm a fan of this club first and foremost, but how bad are things when you find yourself secretly wishing that your own team lost so that just maybe real change would finally come... I resent this team for even making me feel such thoughts and it's going to take a lot of effort on their part to earn my trust again... this club has treated the fans so poorly that it has created an incredibly fragile and toxic environment, so much so that a «what have you done for me lately» mentality has emerged... fans rise and fall depending on the results of each game because we don't have faith in those in charge to make the necessary changes to personnel and tactics... each time we win many fans attack any dissenting voices and make unrealistic claims about the players, the manager and the potential for unprecedented success... every time we lose the boo - birds run rampant, calling for heads to roll and predicting the worst... regardless of what side you fall on, it's not your fault, both sides are simply overcompensating for the horrible state of affairs that have been percolating for several years... it's hard to take the long view when those in charge have lied incessantly and refuse to take any responsibilities for their own actions... in the end, we are trapped by the same catch - 22 that ManU faced upon Fergie's exit... less fearful of maintaining the status quo than facing the unknown, which was validated, wrongly or rightly, by witnessing the difficulties they have faced during this transitory period... to be honest, the thing that scares me most is that this team has never prepared whatsoever for this eventuality, which considering our frugal nature and the way we have shunned many of our most revered former players is more than a little disconcerting

After recently garnering unwanted attention following a nightclub incident during the international break, Wilshere will hope to put this behind him as he gears up for a potential return to first - team action this week, almost a year since his last appearance in the Premier League.

The long - term potential of your actions during this intense process will easily justify any effort you can muster, and then some.

Tory party chairman Baroness Warsi condemns Len McCluskey's comments today about the potential for industrial action during the Olympics

And it says WHO «fed suspicions» about its actions by insisting that Emergency Committee members who gave advice during the pandemic remain confidential and by not revealing their potential conflicts of interest.

The capability of firing action potentials, among other functions of mature neurons, has to be acquired during development and neuronal maturation.

When we overexpress the homeobox transcription factor Dlx2, or the basic helix - loop - helix transcription factor Ascl1, we obtained neurons that exhibited action potential discharges typical for interneurons generated in the medial ganglionic eminence, where these two transcription factors are also expressed during development.

«We found that, during periods of recurrent network activity, cortical pyramidal cells in vivo and in vitro receive strong barrages of both excitatory and inhibitory postsynaptic potentials, with the inhibitory potentials synchronously controlling the timing of action potentials.»

Being aware of potential issues and having a plan of action that prevents them from becoming problems during therapy is what will keep you both happy and healthy.

Some studies have indicated that electroencephalography (EEG)- derived movement - related cortical potentials (MRCPs) are greater during eccentric muscle actions than in concentric contractions (Fang et al. 2001; 2004).

Putting Your Choices Into Action Once you choose your Top 10 Must Haves and Can't Stands, now it's time to put them into action — share them with your matches during the Guided Communication process and reflect on them when you're sitting across the table from your potential partner on the first couple of Action Once you choose your Top 10 Must Haves and Can't Stands, now it's time to put them into action — share them with your matches during the Guided Communication process and reflect on them when you're sitting across the table from your potential partner on the first couple of action — share them with your matches during the Guided Communication process and reflect on them when you're sitting across the table from your potential partner on the first couple of dates.

PARIS, FRANCE — October 30, 2017 — Gamers looking to experience the full potential of PlayStation VR are one step closer today as Polyarc kicks off pre-orders for Moss today, the breakthrough action - adventure puzzle game revealed earlier this year during Sony's 2017 E3 Press Conference.

Denninger became captain by rising through the ranks — though it was his quick actions during a fire that nearly destroyed the ship early in its journey that proved he had leadership potential.

No - one was injured during the work, but the potential for a serious accident was high and the school, as client, took positive action to ensure safe systems of work were employed through the good communication between them and the principal contractor.

According to the social mobility action plan, which is called «unlocking talent, fulfilling potential», the future talent programme will «trial approaches and present clear recommendations on what works» to support «the most able disadvantaged children, particularly during key stage 3 when they so often fall behind».

When that same preservice English teacher reflected on the way a fellow preservice teacher handled a rebellious student during a lesson, I offered some views on authority in the classroom, as well as potential responses to the student's actions:

(39 kg) raise the child into the adult belted zone • Anti-lock brakes (ABS) modulate the brakes for the driver to provide steering control while braking • Electronic Stability Program (ESP) applies selective braking or throttle reduction to control oversteer and understeer • Brake Assist ensures maximum braking action during panic stops • Traction Control reduces the throttle and / or applies selective braking to optimize traction during acceleration • Electronic Roll Mitigation determines when the vehicle is in a potential roll over condition and applies appropriate braking force to reduce the likelihood that such an event will occur • Rollover Sensing deploys seat - mounted side air bags, side - curtain air bags and seat - belt pretensioners • Trailer Sway Control helps maintain vehicle and trailer system stability by applying selective braking • Event Data Recorder records the nature of a malfunction or impact event for retrieval using a service diagnostic tool • Available ParkView ™ Rear Backup Camera displays the view behind the vehicle in the navigation display when backing up or parking • Tire Pressure Monitoring (TPM) alerts drivers to low tire pressure (s) to facilitate safe handling • Brake - park Interlock prevents automatic transaxle from being shifted out of Park or Neutral without first applying brakes • Side Guard Door Beams in front and rear doors provide occupant protection in the event of a side impact

Often a poorly installed / constructed condition that could have been visually reviewed during a construction progress inspection becomes covered or concealed later in the building process cause a potential financial burden for the property owner for future corrective action.

At this time, the U.S. Embassy in Seoul sees no potential danger to American citizens in South Korea as a result of the possible launch and does not believe that any special actions are warranted by American citizens other than to pay close attention to local news reports during this time period.

During E3, Nintendo showed off a lot of action during their Treehouse presentations, I've yet to watch them all, but they all point towards Breath of the Wild being a potential smash hit for NinDuring E3, Nintendo showed off a lot of action during their Treehouse presentations, I've yet to watch them all, but they all point towards Breath of the Wild being a potential smash hit for Ninduring their Treehouse presentations, I've yet to watch them all, but they all point towards Breath of the Wild being a potential smash hit for Nintendo.

PARIS, FRANCE — October 30, 2017 — Gamers looking to experience the full potential of PlayStation VR are one step closer today as Polyarc kicks off pre-orders for Moss today, the breakthrough action - adventure puzzle game revealed earlier this year during Sony's 2017 E3 Press Conference.

If you are the subject of an investigation, or have been summoned before a grand jury, the Strom Law Firm, LLC can investigate the potential charges against you and advise you on the best course of action to take during the investigation.

As such, it is imperative that organizations involve in - house counsel in the process of establishing investigation protocols, as well as during the investigation review process, to ensure that investigative actions can withstand potential challenges from the Ministry of Labour.

Defeated class certification in potential multi-million dollar health care consumer fraud action, then resolved for exceptionally favorable value during the appeal.

In determining the amount and duration of maintenance the court shall consider: (A) the income and property of the respective parties including marital property distributed pursuant to subdivision five of this part; (B) the duration of the marriage and the age and health of both parties; (C) the present and future earning capacity of both parties; (D) the ability of the party seeking maintenance to become self - supporting and, if applicable, the period of time and training necessary therefor; (E) reduced or lost lifetime earning capacity of the party seeking maintenance as a result of having foregone or delayed education, training, employment, or career opportunities during the marriage; (F) the presence of children of the marriage in the respective homes of the parties; (G) the tax consequences to each party; (H) contributions and services of the party seeking maintenance as a spouse, parent, wage earner and homemaker, and to the career or career potential of the other party; (I) the wasteful dissipation of marital property by either spouse; (J) any transfer or encumbrance made in contemplation of a matrimonial action without fair consideration; and (K) any other factor which the court shall expressly find to be just and proper.

If appropriate during quiet times prepare a takeover defence playbook with your advisers, including a list of potential buyers, a draft confidentiality agreement containing a standstill and other precedent disclosure documents, and very importantly a timeline with correlated action items.

Attorneys for both plaintiffs and defendants will find comprehensive coverage of such matters as: the advantages and disadvantages of suits based on strict liability, negligence and breach of warranty; the use of state consumer protection statutes; the duty to warn and its innumerable ramifications; the liability of the manufacturers, retailers and other potential defendants in the distribution chain; successor liability; federal preemption of common law claims; monitoring product safety during design, manufacturing and distribution; causation theories in actions involving multiple manufacturers; product misuse and alteration; the elements of proof needed in an action; recovery for economic loss; punitive damages; and the government contractor defense.

Some called for executives to aggressively pursue action against those leaking to the media, said two Facebook employees, as well as for the company to do more to screen for potential whistle - blowers during the hiring process.

84 DOS 99 Matter of DOS v. Woodland - failure to appear at hearing; jurisdiction; mortgage applications; failure to pay judgment; ex parte hearing may proceeding upon proof of proper service; DOS has jurisdiction over respondents for acts of misconduct which occurred during licensure even though the licenses expired on their own terms; DOS fails its burden of proof to establish broker failed to obtain signature on agency disclosure form; DOS fails its burden of proof to establish that a broker has an obligation to «pre-qualify» a potential purchaser; broker breached duty to deal honestly with the public when advised purchaser he would assist in obtaining financing and failed to do so; DOS fails its burden of proof that broker wrongfully failed to hold a $ 500.00 deposit in escrow as deposit was remitted to seller with the permission of buyer; failure to pay judgment without a showing that broker is unable to do so is a demonstration of untrustworthiness; no action to be taken for reapplication for broker's license until payment of $ 1,000.00 fine and proof of satisfaction of judgment

2d 651)-- remedies provision of the Property Condition Disclosure Act are unenforceable beyond the requirement to give a $ 500 credit at closing should the seller refuse to provide the form, thereafter, common law or statutory remedies, if any, are available; information contained in the disclosure statement survives neither contract nor closing; seller answering «unknown» on the disclosure form triggers a duty to inquire on the part of the buyer and relieves the seller of any potential liability for defects that arise in regard to the part of the premises covered by the question; any information disclosed during the sale of the property merges into the contract and does not exist on its own basis of a common law cause of action; buyer's action based on breach of the disclosure statement is dismissed on the grounds that no such cause of action is created by RPL Article 14; buyer's relief exists under common law contract theories and buyers have not proven their prima faciecase under those theories