Sentences with phrase «during cellular division»
The efficient compaction of DNA during cellular division ensures equal distribution of DNA into daughter cells and prevents aneuploidy, which has been implicated as a major driver of tumor development.
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«Our study on the TACC3 - chTOG interaction will allow cellular biologists and researchers on microtubule dynamics to better understand how microtubule assembly is regulated during cellular division,» says Montoya, and he anticipates that «it could also help in developing new anti-microtubule drugs, providing more effective therapeutic options in cancer treatment.»
The team of researchers uncovered the molecular basis of the interaction between these proteins, and how TACC3 recruits chTOG to the microtubules during cellular division.
Not exact matches
Mutations can be caused by copying errors in the genetic material during cell division and by exposure to radiation, chemicals, or viruses, or can occur deliberately under cellular control during the processes such as meiosis or hypermutation.
The authors uncover the cellular and molecular mechanisms, as well as the gene network regulated by Sox9 during the early steps of skin tumor initiation and demonstrates that Sox9 controls the long term maintenance and expansion of oncogene expressing cells by promoting self - renewing division and inhibiting differentiation.
The DNA vital to the life of a cell is packaged in chromosomes, and a variety of checkpoints, repair mechanisms, and other cellular safeguards exist to maintain the integrity of the chromosomes during cell growth and division.
Needleman is especially interested in the spindle, a cellular structure that separates chromosomes and pulls the duplicated DNA from the mother cell into the daughter cell during division.