267/4: 30 Extremely high resolution 3D maps of human and mouse genomes across lineages and
during differentiation reveal principles of chromatin looping.
Not exact matches
The studies also
revealed when
during taste cell
differentiation these genes influence whether a given taste cell ultimately will respond to either salty, sweet, sour, bitter or umami.
The scientists conclude that the study
reveals an essential function for CTCF in the orchestration of transcriptional changes
during the terminal
differentiation of B lymphocytes and advances understanding of the mechanisms that regulate the immune response.
Their findings outlined four distinct cellular phases of sperm stem cells maturation,
revealing how the stem cells progress from a «quiescent» state, to a «proliferation» state
during which stem cells divide, to a final «
differentiation» state when stem cells mature to become sperm.
Recent studies have started to map the gene - wide chromatin interactions in the interphase nucleus,
revealing some principles of chromosome organization into territories, and dramatic changes of chromatin organization and interactions
during differentiation and lineage specification.
Endogenous optical signals
reveal changes of elastin and collagen organization
during differentiation of mouse embryonic stem cells.
Title: A genome - wide RNAi screen
reveals MAP kinase phosphatases as key ERK pathway regulators
during embryonic stem cell
differentiation (IN PRESS, Oct 2012) Authors: Sharrocks A, Yang S - H, Kalkan T, Haslam C, Smith A Date: IN PRESS, Oct 2012 Publication Details: PLoS Genetics