Sentences with phrase «during early steps»

During this webinar, we will also discuss the molecular events that regulate the biogenesis of autophagosomes in mammals, notably during early steps of autophagy, such as emergence of omegasomes and phagophores.

The crystal structure of the enzyme PvHCT from switchgrass (Panicum vulgare) in complex with coenzyme A (CoA) and p - coumaroyl shikimate (5FAL) gives insight into its catalyzing action during the early steps of lignin biosynthesis.

The authors uncover the cellular and molecular mechanisms, as well as the gene network regulated by Sox9 during the early steps of skin tumor initiation and demonstrates that Sox9 controls the long term maintenance and expansion of oncogene expressing cells by promoting self - renewing division and inhibiting differentiation.

Not exact matches

Earlier on Thursday, Disney emphasized the importance of keeping Iger on during the transition even though he had planned to step down in mid-2019.

Note: The formats available to you will vary based on the objective you set for your advert during Step 3 a little earlier in this post.

«During early adolescence, the majority of girls stop raising their hands, participating in sports and extra-curricular activities, taking risks, and stepping into leadership roles,» says Catherine Connors, the company's co-founder and chief content officer.

«During many physical tasks, children might tire earlier than adults because they have limited cardiovascular capability, tend to adopt less - efficient movement patterns and need to take more steps to move a given distance.

Although Fed officials took strong steps early in the year, including cutting the central bank's benchmark interest rate by more than half during the first four months, it took until the fall for them to realize that the economy had fallen into a severe recession.

Priestless parishes thrived in Maryland, Pennsylvania and New York in the early years of the Republic when independent laymen stepped forward with the resources and talent needed to sustain Catholic identity during a time of organizational immaturity.

However, our interest lies in these early season tournaments meaning the next step was to use the «game month» filter to focus on all neutral site games played during November.

Izzo received heat during the Larry Nassar trial for issuing his support for former MSU President Lou Anna Simon, who stepped down earlier this week but will receive her salary for two years and a lifetime of perks:

The final step (which is the only one that should be expected to last past the early twos) is a raisin for staying dry during the day and a chocolate chip for the night / for both day and night.

In this online do - it - yourself program, I've shared my unique 12 - step, 12 - week Potty Savvy method of early potty learning (for tots 10 - 18mo) with tips after tips, ranging from what look for when selecting a potty to how to make potty time fun to addressing various challenges many parents face during the potty learning process.

We ensured that the right messages with the right tone were being provided to mums during pregnancy and early childhood, to make sure SMA was supporting mums every step of the way.

If your baby is under 8 months old and you think he is waking up very early because he is hungry, try waking him for a final feeding about 11:00 p.m. as an interim step, and also work on making sure he takes more food during the day.

During pregnancy, thinking about and planning ahead for those early weeks after the birth of your baby are important steps which will help you be better prepared.

An infant must learn to attach and suckle properly at the breast during the first few days of life to successfully establish breastfeeding.1,, 2 Early oral experiences that require sucking mechanics different from those required for breastfeeding are believed to contribute to the development of improper latch and subsequent breastfeeding failure — a problem described as nipple confusion.2 — 4 The avoidance of pacifiers was included as 1 of 10 steps for successful breastfeeding in the 1990 Innocenti Declaration on maternity services and breastfeeding, and many experts recommend that mothers who are breastfeeding avoid exposing their infants to artificial suckling experiences including use of pacifiers.5 — 7

These steps may need to be repeated frequently during the early weeks.

Because Mayor Bill de Blasio «can't manage the homeless crisis» in New York City, Gov. Andrew Cuomo plans to «step in,» and will unveil a new plan to address homelessness during his state of the state address in early January, his office said Wednesday.

MANHATTAN — City Councilman Ydanis Rodriguez, freshly shaved and showered, told reporters on the steps of City Hall that he was beaten and thrown to the ground by a police officer when he was arrested during a police sweep of Zuccotti Park early Tuesday morning.

Astorino lit into Christie on Tuesday during an earlier appearance on Dicker's show, saying that the New Jersey governor should step down from the RGA if he's refusing to support other Republican candidates.

«These organoids provide a major step forward in investigating the changes that occur during the menstrual cycle and events during early pregnancy when the placenta is established,» says Dr Margherita Turco, the study's first author.

«This study takes an important step» toward resolving why horses shed digits during their early evolution, says Karen Sears, an evolutionary biologist at UCLA.

These findings could be a step in grasping how the brain circuit is shaped during this early stage development and how these neuronal circuits contribute to higher cognitive function in adulthood.

Although he was bitten by the biology bug early on, he stepped off the track to a research career entirely during a difficult period in his training.

While the observed differences of the individual steps were mostly modest, mathematical modeling suggested that even small delays in the trafficking of these immune cells will lead to reduced initiation of a WNV - specific antibody - response during the early stages after infection.

The addition of the fossil to existing data on ancient turtles solidifies the theory that changes to the ribs and vertebrae were early steps in shell evolution and occurred during the Permian geological period, when early mammal, bird, and crocodile relatives were also diversifying.

Earlier this year, Kiyomitsu, working in Cheeseman's lab, saw that during the metaphase cell cycle step a dividing cell uses the motor protein dynein and two signals to perfectly align the cell's mitotic spindle structure in the middle of the cell.

As a result we now have an appropriate human cell system with which to address the mechanisms of telomere regulation during cellular aging and the early steps of tumor formation.

Overall, our transcriptome analyses indicated that, whereas the iPSCs are globally similar to hESCs, they are not indistinguishable, primarily due to the insufficient suppression or induction of NSC - specific or early embryonic - specific genes, respectively, as well as a class of genes that was upregulated during the reprogramming step.

In this study, they examined anti-correlations of different subnetworks within the DMN during rest using both seed - based and point process analyses, and discovered that: (1) the ventral branch of the DMN (vDMN) yielded significantly weaker anti-correlations than that associated with the dorsal branch of the DMN (dDMN); (2) vDMN anti-correlations introduced by GSR were distinct from dDMN anti-correlations; (3) PCC / precuneus seeds employed by earlier studies mapped to different DMN subnetworks, which may explain some of the inconsistency (in addition to preprocessing steps) in the reported DMN anti-correlations.

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PARIS, FRANCE — October 30, 2017 — Gamers looking to experience the full potential of PlayStation VR are one step closer today as Polyarc kicks off pre-orders for Moss today, the breakthrough action - adventure puzzle game revealed earlier this year during Sony's 2017 E3 Press Conference.

Because experiences during the early school years lay the foundation for ongoing peer relationships and can include a pattern of being bullied, we've created the Bullying Prevention Unit, basing it on the latest research and evalution, including a recent study of our Steps to Respect program.

Steps to prevent eclampsia in the bitch include feeding a high - quality, nutritionally balanced, and appropriate diet during pregnancy and lactation, providing food and water ad lib during lactation, and supplemental feeding of the puppies with milk replacer early in lactation and with solid food after 3 - 4 wk of age.

Because of the more serious nature of the game mode, strict penalties will be in place to catch people leaving the game early or even stepping away from their console during the match, so ensure you make that all important toilet break.

PARIS, FRANCE — October 30, 2017 — Gamers looking to experience the full potential of PlayStation VR are one step closer today as Polyarc kicks off pre-orders for Moss today, the breakthrough action - adventure puzzle game revealed earlier this year during Sony's 2017 E3 Press Conference.

The same could be said for Dr. Games, a Doctor who stepped in to fill the same role during 1984 but had early retirement that same year for its lack of appeal, restoring the throne to the same Prof. Asobin.

The Wall Street Journal reiterated that this plan is still in its early stages, and the console's performance during the holiday months will greatly influence what steps will be taken moving forward.

During Titanfall 2's multiplayer beta earlier this year, there was a lot of fan outcry calling it a step backwards, with many feeling it took too long for the losing team to be given access to Titan drops, among other balancing qualms.

According to the guidelines in the exhibition, «while the dancer performs, visitors become bystanders and etiquette decrees that during that time, no one except the performer can set foot in the space», and the way the visitors are guided to circulate is reminiscent of Bronstein's earlier work, Concept for a Public Square (2005) where visitors could not step across, but had to skirt around a low wall demarcating an area of dead space.

The watch didn't have a release date as it was still very early but it was initially announced by Swarovski back during CES in the beginning of this year, and although the plans for its further development are now taking an indefinite break, Swarovski doesn't seem to have given any in - depth explanation as to why they are choosing to take a step back from entering the smartwatch market with their own Android Wear offering.

Earlier this summer, he announced plans to step down as CEO sometime during the next year.

It was another step on the company's journey to dissolve its phone hardware business; earlier this year, its quarterly phone revenue collapsed to just $ 5 million, down from $ 1.4 billion two years before, and during the most recent quarter, Microsoft described its phone revenue as «immaterial».

Writing a finance resume is one of the initial steps that you need to focus on during the early stages of your application.

Logistic regression analyses were conducted to investigate the mediation hypotheses, using an established 3 - step procedure.48 First, we investigated whether there was a significant bivariate association between a high level of maladaptive parenting (operationally defined as ≥ 3 maladaptive parenting behaviors) or abuse during childhood or early adolescence (by a mean age of 14 years) and risk for suicide attempts during late adolescence or early adulthood (reported at a mean age of 22 years) and whether the magnitude of this association was reduced when interpersonal difficulties during middle adolescence (reported at a mean age of 16 years) were controlled statistically.

Picture this... You blissfully awaken to the soft rays of the sun warming your face... step out of your oversized guest room onto your lanai to delight in the tropical surroundings... take an early morning stroll along the sandy beach, hand - in - hand with your spouse... then head over to the elegant Ritz - Carlton ballroom to sing praises to the Lord during morning worship led by MercyMe, followed by a teaching from Dr. Gary Chapman, author of The 5 Love Languages... then it's off to the pool to take a dip in the refreshing aqua blue pool... and that's just the beginning!

Majority owner Scholz said he «fell in love with the place» and stepped in during 2011 to forge a deal with the developer, purchasing the majority of units that had not sold earlier.