Since the signalling mechanisms affected in these diseases are the same mechanisms that occur
during embryonic heart development, their study is a subject of great interest and relevance.
Not exact matches
In his postdoctoral training at Metrohealth Medical Center, Duke University Medical Center, and Mt. Sinai Medical Center, he has been interested in the maintenance of electrical function in the
heart during embryonic development and in
heart failure models.
They found that groups of genes appear to work together in
heart cells in a coordinated fashion — switching on and off as a group at designated times
during embryonic development.
In a similar manner, the induction of hematopoietic (cluster 20, day 3.5 +4 = E7.5) and cardiovascular - specific (cluster 12, 3.5 +5 = E8.5) genes follows the chronological order of the appearance of blood islands and the formation of the
heart tube
during embryonic development [50], [51].
During that time, she applied her knowledge of the processes governing normal
heart development to direct the differentiation of
embryonic stem cells into the cardiac lineage.
On rare occasions ectopic thyroid tissue (abnormal migration of thyroid tissue
during embryonic development) can give rise to lesions in the tongue, ventral neck, cranial mediastinum and
heart base.